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How to get fromSaint Louis County to Lexingtonby plane, car, or bus

Find Transport to Lexington

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There are 8 ways to get from Saint Louis County to Lexington by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport, drive

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 40m
    $118–675

  2. Drive 352 mi

    cheapest
    1. Drive from Saint Louis County to Lexingtoncar car 352 mi
    5h 59m
    $65–93

  3. Bus, drive

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Corydon, INbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    11h 36m
    $131–200

  4. Fly to Covington, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    2. Drive from Covington (CVG) to Lexingtoncar car
    6h 31m
    $619–976

  5. Fly to Blue Grass Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    8h 15m
    $186–1,006

  6. Bus, drive via Ballas Transit Center

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Corydon, INbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    11h 40m
    $131–200

  7. Bus, drive #2

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Corydon, INbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    12h 25m
    $129–198

  8. Bus, drive via Louisville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Corydon, INbus bus
    3. Drive from Middletown Station @ Target to Lexingtoncar car
    12h 42m
    $132–198

Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) flights

Calendar112Weekly Planes
Duration4h 36mAverage Duration
Ticket$105Cheapest Price
See schedules

Questions & Answers

Map of how to get from Saint Louis County to Lexington.ExpandLaunch map view
  • Distance: 351 mi
  • Duration: 6h 40m

What companies run services between Saint Louis County, MO, USA and Lexington, KY, USA?

American Airlines, United Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX) hourly.

Airlines
Bus operators

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