There are 6 ways to get from Saint-Louis to Lyon by train (TGV), bus, rideshare, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (TGV)
best- Take the train from Mulhouse Ville to Lyon Part Dieutrain Tgv
4h 20m€84–139Rideshare
cheapest- Take the rideshare from Saint-Louis to Lyon366 km
4h 24m€23–40Bus
- Take the bus from Mulhouse to Lyonbus FlixBus N1135 / ...
5h 48m€34–69Fly
- Fly from Basel (BSL) to Lyon–Saint Exupéry Airport (LYS)plane BSL - LYS
6h 16m€135–255Train, bus
- Take the train from Basel SBB to Lausannetrain Ic51
- Take the bus from Lausanne Bus Station to Lyon Perrache Bus Stationbus : Lyon - Prague Central Bus Station / ...
8h 7m€83–221Drive 365.1 km
- Drive from Saint-Louis to Lyoncar 365.1 km
4h 29m€56–81
Saint-Louis to Lyon by train (TGV)
Questions & Answers
The cheapest way to get from Saint-Louis to Lyon is to rideshare which costs €23 - €40 and takes 4h 24m.
The fastest way to get from Saint-Louis to Lyon is to train which takes 4h 20m and costs €80 - €140.
No, there is no direct bus from Saint-Louis to Lyon. However, there are services departing from Mulhouse and arriving at Lyon via . The journey, including transfers, takes approximately 5h 48m.
No, there is no direct train from Saint-Louis to Lyon. However, there are services departing from St Louis and arriving at Lyon Part Dieu via Mulhouse Ville. The journey, including transfers, takes approximately 4h 20m.
The distance between Saint-Louis and Lyon is 423 km. The road distance is 365.1 km.
The best way to get from Saint-Louis to Lyon without a car is to train which takes 4h 20m and costs €80 - €140.
It takes approximately 4h 20m to get from Saint-Louis to Lyon, including transfers.
Saint-Louis to Lyon bus services, operated by FlixBus, depart from Mulhouse station.
Saint-Louis to Lyon train services, operated by TGV inOui, depart from Mulhouse Ville station.
The best way to get from Saint-Louis to Lyon is to train which takes 4h 20m and costs €80 - €140. Alternatively, you can bus, which costs €30 - €70 and takes 5h 48m, you could also fly, which costs €130 - €260 and takes 6h 16m.
What companies run services between Saint-Louis, Grand Est, France and Lyon, France?
TGV inOui operates a train from Mulhouse Ville to Lyon Part Dieu every 3 hours. Tickets cost €80–130 and the journey takes 3h 7m. Alternatively, FlixBus operates a bus from Mulhouse to Lyon every 4 hours. Tickets cost €30–55 and the journey takes 4h 35m. BlaBlaCar Bus also services this route twice daily.
- Website
- airfrance.com
Flights from Basel to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €55–320
Flights from Basel to Lyon–Saint Exupéry Airport via Nice
- Ave. Duration
- 3h 20m
- When
- Monday and Wednesday
- Estimated price
- €150–240
Flights from Basel to Lyon–Saint Exupéry Airport via Calvi
- Ave. Duration
- 4h 30m
- When
- Saturday
- Estimated price
- €150–240
Flights from Basel to Lyon–Saint Exupéry Airport via Bastia
- Ave. Duration
- 4h 45m
- When
- Saturday
- Estimated price
- €150–240
- Website
- lufthansa.com
Flights from Basel to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €100–600
Flights from Basel to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 4h
- When
- Monday and Friday
- Estimated price
- €100–380
- Website
- aircorsica.com
Flights from Basel to Lyon–Saint Exupéry Airport via Bastia
- Ave. Duration
- 4h 45m
- When
- Saturday
- Estimated price
- €150–240
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Mulhouse Ville to Lyon Part Dieu
- Ave. Duration
- 3h 7m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- TGV inOui
Train from Basel SBB to Lausanne
- Ave. Duration
- 2h 24m
- Frequency
- Hourly
- Estimated price
- €60–190
- Website
- Swiss Federal Railways (SBB CFF FFS)
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mulhouse to Lyon
- Ave. Duration
- 4h 35m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mulhouse to Lyon
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- BlaBlaCar Bus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Lausanne Bus Station to Lyon Perrache Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice a week
- Estimated price
- €16–23
- Website
- RegioJet
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar
Rideshare from Saint-Louis to Lyon
- Ave. Duration
- 4h 24m
- Frequency
- Once a week
- Estimated price
- €23–40
- Schedules at
- BlaBlaCar
Want to know more about travelling around France
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More Questions & Answers
Saint-Louis to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Saint-Louis to Lyon train services, operated by TGV inOui, arrive at Lyon Part Dieu station.
Yes, the driving distance between Saint-Louis to Lyon is 365 km. It takes approximately 4h 29m to drive from Saint-Louis to Lyon.
Book your Saint-Louis to Lyon train tickets online with Omio.
Book your Saint-Louis to Lyon bus tickets online with Omio.
There are 4114+ hotels available in Lyon.
Check out Blablacar's carpooling service for rideshare options between Saint-Louis and Lyon. A great option if you don't have a driver's licence or want to avoid public transport.

















