There are 5 ways to get from Saint Louis University to Chicago by plane, train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
3h 21m$64–408Bus (Flixbus)
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus N2521 / ...
7h 19m$51–81Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
6h 8m$152–242Drive 295.2 mi
- Drive from Saint Louis University to Chicagocar 295.2 mi
5h 6m$51–73Fly to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
3h 46m$324–708
Saint Louis University to Chicago by foot and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Saint Louis University to Chicago is to bus which costs $50 - $85 and takes 7h 19m.
The fastest way to get from Saint Louis University to Chicago is to fly which takes 3h 21m and costs $60 - $410.
No, there is no direct bus from Saint Louis University to Chicago station. However, there are services departing from Lindell @ Grand Eb and arriving at Chicago Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 7h 19m.
No, there is no direct train from Saint Louis University station to Chicago station. However, there are services departing from GRAND station and arriving at Chicago Union Station via St. Louis. The journey, including transfers, takes approximately 6h 8m.
The distance between Saint Louis University and Chicago is 277 miles. The road distance is 296.9 miles.
The best way to get from Saint Louis University to Chicago without a car is to train which takes 6h 8m and costs $150 - $250.
It takes approximately 3h 21m to get from Saint Louis University to Chicago, including transfers.
Saint Louis University to Chicago bus services, operated by Flixbus USA, depart from St Louis Bus Station.
Saint Louis University to Chicago train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Saint Louis University to Chicago is to fly which takes 3h 21m and costs $60 - $410. Alternatively, you can train, which costs $150 - $250 and takes 6h 8m, you could also bus, which costs $50 - $85 and takes 7h 19m.
What companies run services between Saint Louis University, MO, USA and Chicago, IL, USA?
Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $150–240 and the journey takes 4h 55m.
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–280
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $60–400
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $40–280
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–280
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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Booking & Getting There
Saint Louis University to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Saint Louis University to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Saint Louis University to Chicago is 297 miles. It takes approximately 5h 6m to drive from Saint Louis University to Chicago.
There are 1310+ hotels available in Chicago.