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How to get fromSaint Paul to Des Moinesby plane, bus (Greyhound), or car

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There are 3 ways to get from Saint Paul to Des Moines by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane plane MSP - DSM
    2h 50m
    $99–574
  2. Drive 244.2 mi

    cheapest
    1. Drive from Saint Paul to Des Moinescar car 244.2 mi
    4h
    $45–65
  3. Bus

    1. Take the bus from Saint Paul Union Depot to Des Moinesbus bus Greyhound US0156
    5h 30m
    $60–90

Saint Paul to Des Moines by bus

Calendar9Weekly Buses
Duration5h 30mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

What companies run services between Saint Paul, MN, USA and Des Moines, IA, USA?

Delta flies from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM) 4 times a day. Alternatively, Greyhound USA operates a bus from Saint Paul Union Depot to Des Moines 5 times a week. Tickets cost $35–75 and the journey takes 5h 30m. Jefferson Lines also services this route 4 times a week.

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