Rome2Rio

How to get fromSaint Paul to Indianapolisby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Flixbus)

Find Transport to Indianapolis

See all options

There are 5 ways to get from Saint Paul to Indianapolis by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Indianapolis (IND)plane plane MSP - IND
    4h 7m
    $104–654

  2. Bus

    cheapest
    1. Take the bus from Saint Paul Union Depot to Chicago Bus Stationbus bus Greyhound US0150
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    12h 45m
    $96–159

  3. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    13h 26m
    $325–515

  4. Drive  577.4 mi

    1. Drive from Saint Paul to Indianapoliscar car 577.4 mi
    9h 41m
    $99–143

  5. Bus via Madison

    1. Take the bus from Minneapolis to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Bus Station to Indianapolisbus bus
    17h 18m
    $117–207

Saint Paul to Indianapolis by bus

Calendar56Weekly Buses
Duration12h 45mAverage Duration
Ticket$96Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Saint Paul to Indianapolis.ExpandLaunch map view
  • Distance: 523.3 mi
  • Duration: 4h 7m

What companies run services between Saint Paul, MN, USA and Indianapolis, IN, USA?

Delta, Sun Country Airlines, and two other airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Indianapolis (IND) every 4 hours. Alternatively, you can take a bus from Saint Paul Union Depot to Indianapolis via Chicago Bus Station in around 12h 45m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There