There are 9 ways to get from Saint Simons Island to Florida Keys by plane, taxi, bus, train, car, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Brunswick Golden Isles Airport to Key West International Airport
best- Fly from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW)plane BQK - EYW
8h$183–493Drive 563.9 mi
cheapest- Drive from Saint Simons Island to Florida Keyscar 563.9 mi
10h 5m$103–149Taxi, bus
- Take the taxi from Saint Simons Island to Woodbinetaxi
- Take the bus from Woodbine to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
15h 29m$162–234Taxi, train, bus
- Take the taxi from Saint Simons Island to Jesup Stationtaxi
- Take the train from Jesup Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
18h 54m$259–470Drive to Savannah, fly to Miami International Airport, shuttle
- Drive from Saint Simons Island to Savannah (SAV)car
- Fly from Savannah (SAV) to Miami International Airport (MIA)plane SAV - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
8h 28m$247–705Bus to Jacksonville, fly to Key West International Airport
- Take the bus from Brunswick to Jacksonvillebus
- Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane JAX - EYW
10h 16m$177–437Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Saint Simons Island to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
7h 45m$149–397Bus
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
16h$132–203Bus, shuttle
- Take the bus from Brunswick to Orlando Bus Stationbus
- Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
16h 54m$284–375
Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Saint Simons Island to Florida Keys is to drive which costs $100 - $150 and takes 10h 5m.
The fastest way to get from Saint Simons Island to Florida Keys is to drive and fly which takes 7h 45m and costs $140 - $400.
No, there is no direct bus from Saint Simons Island to Florida Keys. However, there are services departing from Brunswick and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Orlando Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 16h.
The distance between Saint Simons Island and Florida Keys is 502 miles. The road distance is 567.2 miles.
The best way to get from Saint Simons Island to Florida Keys without a car is to taxi and bus which takes 15h 29m and costs $160 - $240.
It takes approximately 8h to get from Saint Simons Island to Florida Keys, including transfers.
Saint Simons Island to Florida Keys bus services, operated by Flixbus USA, depart from Brunswick station.
The best way to get from Saint Simons Island to Florida Keys is to fly which takes 8h and costs $180 - $500. Alternatively, you can bus, which costs $130 - $210 and takes 16h.
Saint Simons Island to Florida Keys bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Saint Simons Island to Florida Keys is 567 miles. It takes approximately 10h 5m to drive from Saint Simons Island to Florida Keys.
What companies run services between Saint Simons Island, GA, USA and Florida Keys, FL, USA?
Delta flies from Brunswick Golden Isles Airport (BQK) to Key West International Airport (EYW) 4 times a day. Alternatively, you can take a vehicle from Saint Simons Island to Florida Keys via Brunswick, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 16h.
- Website
- aa.com
Flights from Savannah to Miami International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $80–500
Flights from Jacksonville to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 46m
- When
- Monday, Thursday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- $45–270
Flights from Jacksonville to Key West International Airport via Charlotte
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $75–360
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jesup Station to Hollywood Amtrak Station
- Ave. Duration
- 10h 34m
- Frequency
- Once daily
- Estimated price
- $120–290
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Woodbine to Miami Airport Station
- Ave. Duration
- 8h 40m
- Frequency
- 4 times a week
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Brunswick to Jacksonville
- Ave. Duration
- 1h
- Frequency
- 6 times a week
- Estimated price
- $9–14
- Schedules at
- Flixbus USA
Bus from Brunswick to Orlando Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Brunswick to Orlando Bus Station
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
- Ave. Duration
- 51 min
- Estimated price
- $80–140
Latino Taxi
- Phone
- +1 912-289-4732
- Website
- latinotaxi.com
Metro Cab
- Phone
- +1 912-554-2000
- Website
- metrocabbrunswick.com
On Time Taxi
- Phone
- +1 912-506-2683
- Website
- ontimetaxijamaica.com
Latino Taxi
- Phone
- +1 912-289-4732
- Website
- latinotaxi.com
Metro Cab
- Phone
- +1 912-554-2000
- Website
- metrocabbrunswick.com
On Time Taxi
- Phone
- +1 912-506-2683
- Website
- ontimetaxijamaica.com
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There are 969+ hotels available in Florida Keys.




