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How to get fromSaint Simons Island to Port Saint Lucieby bus (Flixbus), car, plane, taxi, bus, bus (Greyhound, Flixbus), or train

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There are 7 ways to get from Saint Simons Island to Port Saint Lucie by bus (Flixbus), car, plane, taxi, bus, bus (Greyhound, Flixbus), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Orlando

    best
    1. Take the bus from Brunswick to Orlando Bus Stationbus bus FlixBus 2434
    2. Take the bus from Orlando to Fort Piercebus bus Orlando to Miami
    8h 30m
    $107–151

  2. Drive 309.9 mi

    cheapest
    1. Drive from Saint Simons Island to Port Saint Luciecar car 309.9 mi
    5h 15m
    $57–82

  3. Fly Brunswick Golden Isles Airport to Melbourne International Airport, taxi, bus

    1. Fly from Brunswick Golden Isles Airport (BQK) to Melbourne International Airport (MLB)plane plane BQK - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    9h 34m
    $202–552

  4. Bus

    1. Take the bus from Brunswick to Jacksonvillebus bus Greyhound US0640s
    2. Take the bus from Jacksonville to Port St Luciebus bus Greyhound US0710s
    10h 22m
    $89–147

  5. Bus, train

    1. Take the bus from Brunswick to Jacksonvillebus bus
    2. Take the train from Jacksonville to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    10h 45m
    $137–227

  6. Drive to Savannah, fly to Miami International Airport, bus

    1. Drive from Saint Simons Island to Savannah (SAV)car car
    2. Fly from Savannah (SAV) to Miami International Airport (MIA)plane plane SAV - MIA
    3. Take the bus from Sheridan Tri-Rail Station to Fort Piercebus bus
    6h 57m
    $123–517

  7. Fly Brunswick Golden Isles Airport to President Donald J. Trump International Airport, bus

    1. Fly from Brunswick Golden Isles Airport (BQK) to President Donald J. Trump International Airport (PBI)plane plane BQK - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    8h 48m
    $140–516

Brunswick Golden Isles Airport (BQK) to Melbourne International Airport (MLB) flights

Calendar35Weekly Planes
Duration7h 37mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Saint Simons Island to Port Saint Lucie.ExpandLaunch map view
  • Distance: 345.7 mi
  • Duration: 8h 30m

What companies run services between Saint Simons Island, GA, USA and Port Saint Lucie, FL, USA?

You can take a vehicle from Saint Simons Island to Fort Pierce via Brunswick, Orlando Bus Station, John Young Pkwy & Amelia St, N Garland Ave & W Amelia St, L B Mcleod Rd & Gardenia Ave, and Orlando in around 8h 30m.

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