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How to get fromSaint Simons Island to St. Louisby plane, bus (Flixbus, Greyhound), car, or bus

Find Transport to St. Louis

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There are 6 ways to get from Saint Simons Island to St. Louis by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Brunswick Golden Isles Airport

    best
    1. Fly from Brunswick Golden Isles Airport (BQK) to Lambert–St. Louis International Airport (STL)plane plane BQK - STL
    5h 37m
    $144–602

  2. Drive to Hilton Head Airport, fly

    cheapest
    1. Drive from Saint Simons Island to Hilton Head Airport (HHH)car car
    2. Fly from Hilton Head Airport (HHH) to Lambert–St. Louis International Airport (STL)plane plane HHH - STL
    8h 3m
    $124–584

  3. Bus

    1. Take the bus from Brunswick to Atlanta Bus Stationbus bus FlixBus 2434
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    17h 4m
    $180–294

  4. Drive  827.3 mi

    1. Drive from Saint Simons Island to St. Louiscar car 827.3 mi
    14h 37m
    $151–219

  5. Drive to Savannah, fly

    1. Drive from Saint Simons Island to Savannah (SAV)car car
    2. Fly from Savannah (SAV) to Lambert–St. Louis International Airport (STL)plane plane SAV - STL
    4h 20m
    $148–774

  6. Bus to Jacksonville, fly

    1. Take the bus from Brunswick to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane plane JAX - STL
    7h 6m
    $158–627

Brunswick Golden Isles Airport (BQK) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration5h 33mAverage Duration
Ticket$100Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Saint Simons Island to St. Louis.ExpandLaunch map view
  • Distance: 749.8 mi
  • Duration: 5h 37m

What companies run services between Saint Simons Island, GA, USA and St. Louis, MO, USA?

Delta flies from Brunswick Golden Isles Airport (BQK) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a vehicle from Saint Simons Island to St Louis Bus Station via Brunswick and Atlanta Bus Station in around 17h 4m.

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