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How to get fromSalar de Uyuni to Santa Cruzby unknown, plane, car, or bus

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There are 4 ways to get from Salar de Uyuni to Santa Cruz by unknown, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Travel, fly

    best
    1. Walk from Salar de Uyuni to Uyuni Airport (UYU)unknown unknown
    2. Fly from Uyuni Airport (UYU) to Viru Viru International Airport (VVI)plane plane UYU - VVI
    5h 46m

  2. Travel, Tour, bus

    1. Walk from Salar de Uyuni to Isla Incahuasiunknown unknown
    2. Drive from Isla Incahuasi to Uyunicar car
    3. Take the bus from Uyuni to Sucrebus bus
    4. Take the bus from Sucre to Santa Cruzbus bus
    15h 26m

  3. Travel, Tour, bus via Samaipata

    1. Walk from Salar de Uyuni to Isla Incahuasiunknown unknown
    2. Drive from Isla Incahuasi to Uyunicar car
    3. Take the bus from Uyuni to Sucrebus bus
    4. Take the bus from Sucre to Samaipatabus bus
    5. Take the bus from Samaipata to Santa Cruzbus bus
    22h 31m

  4. Travel, Tour, bus via Sucre

    1. Walk from Salar de Uyuni to Isla Incahuasiunknown unknown
    2. Drive from Isla Incahuasi to Uyunicar car
    3. Take the bus from Uyuni to Sucrebus bus
    4. Take the bus from Sucre to Santa Cruzbus bus
    24h 26m

Uyuni Airport (UYU) to Viru Viru International Airport (VVI) flights

Calendar11Weekly Planes
Duration4h 41mAverage Duration
Ticket$217Cheapest Price
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Questions & Answers

Map of how to get from Salar de Uyuni to Santa Cruz.ExpandLaunch map view
  • Distance: 594.4 km
  • Duration: 5h 46m

What companies run services between Salar de Uyuni, Bolivia and Santa Cruz, Bolivia?

There is no direct connection from Salar de Uyuni to Santa Cruz. However, you can travel to Uyuni Airport (UYU) airport, fly to Viru Viru International Airport (VVI), walk to Aeropuerto Internacional Viru Viru, then take the line 135 bus to Santa Cruz - Ex Terminal. Alternatively, you can take a vehicle from Salar de Uyuni to Santa Cruz de la Sierra via Isla Incahuasi, Uyuni, Uyuni, Sucre, and Santa Cruz in around 15h 26m.

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