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How to get fromSalem to Buffaloby train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Salem to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Salem to Chelseatrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    4h 21m
    $85–542

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Boston to Buffalobus bus Greyhound US0171
    12h 41m
    $73–149

  3. Train (Amtrak)

    1. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    14h 40m
    $158–482

  4. Drive 467.2 mi

    1. Drive from Salem to Buffalocar car 467.2 mi
    8h 19m
    $86–124

  5. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 1m
    $117–607

  6. Bus via Ithaca

    1. Take the bus from Boston to Ithacabus bus FlixBus 2691
    2. Take the bus from Ithaca to Buffalobus bus FlixBus N2687 / ...
    14h 16m
    $91–223

Salem to Buffalo by bus and foot (Greyhound)

Calendar7Weekly Services
Duration12h 41mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

Map of how to get from Salem to Buffalo.ExpandLaunch map view
  • Distance: 424.3 mi
  • Duration: 4h 21m

What companies run services between Salem, MA, USA and Buffalo, NY, USA?

Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $70–140 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $150–330 and the journey takes 11h 32m.

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