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How to get fromSalem to Louisvilleby plane, bus (Flixbus), train, bus, car, or bus (Greyhound, Amtrak)

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There are 7 ways to get from Salem to Louisville by plane, bus (Flixbus), train, bus, car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    5h 43m
    $124–666

  2. Bus via Columbus

    1. Take the bus from Boston to NYC Downtownbus bus
    2. Take the bus from New York, NY to Columbus, OHbus bus Nyc
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    23h 27m
    $166–237

  3. Train, bus via Toledo

    1. Take the train from Boston to Toledotrain train
    2. Take the bus from Toledo to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    27h 33m
    $289–672

  4. Drive 950.6 mi

    1. Drive from Salem to Louisvillecar car 950.6 mi
    17h 17m
    $174–251

  5. Fly to Covington, bus

    1. Fly from Boston Logan Airport (BOS) to Covington (CVG)plane plane BOS - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    8h 13m
    $414–1,060

  6. Bus

    1. Take the bus from Boston to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    27h 41m
    $175–353

  7. Train, bus (Amtrak)

    1. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    33h 7m
    $378–1,457

Salem to Louisville by bus, foot, and subway

Calendar7Weekly Services
Duration23h 27mAverage Duration
Ticket$166Cheapest Price
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Questions & Answers

Map of how to get from Salem to Louisville.ExpandLaunch map view
  • Distance: 849.3 mi
  • Duration: 5h 43m

What companies run services between Salem, MA, USA and Louisville, KY, USA?

American Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from North St @ Essex St to Louisville, KY Bus Station via Congress St @ Haymarket Sta, Downtown Crossing, South Station, Boston, NYC Downtown, New York, NY, Columbus, OH, and Columbus - Downtown - Mound St in around 23h 27m.

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