Rome2Rio

How to get fromSalem to Knoxvilleby bus, plane, train, or car

Find Transport to Knoxville

See all options

There are 9 ways to get from Salem to Knoxville by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Portland International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Salem Amtrak Station to Portland International Airportbus bus
    2. Fly from Portland International Airport (PDX) to Mcghee Tyson Airport (TYS)plane plane PDX - TYS
    8h 59m
    $341–1,191
  2. Bus to Portland International Airport, fly to Nashville, drive

    cheapest
    1. Take the bus from Salem Amtrak Station to Portland International Airportbus bus
    2. Fly from Portland International Airport (PDX) to Nashville (BNA)plane plane PDX - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    9h 37m
    $196–771
  3. Train, bus

    1. Take the train from Salem to Portlandtrain train
    2. Take the train from Portland to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 11h
    $1,155–2,347
  4. Drive 2,541 mi

    1. Drive from Salem to Knoxvillecar car 2,541 mi
    41h 26m
    $464–670
  5. Train to Mahlon Sweet Field Airport, fly to Mcghee Tyson Airport

    1. Take the train from Salem to Eugenetrain train
    2. Fly from Mahlon Sweet Field Airport (EUG) to Mcghee Tyson Airport (TYS)plane plane EUG - TYS
    10h 11m
    $339–1,223
  6. Bus to Roberts Field-Redmond Municipal Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Salem Amtrak Station to Redmond Airportbus bus
    2. Fly from Roberts Field-Redmond Municipal Airport (RDM) to Mcghee Tyson Airport (TYS)plane plane RDM - TYS
    10h 43m
    $301–1,070
  7. Bus to Portland International Airport, fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Take the bus from Salem Amtrak Station to Portland International Airportbus bus
    2. Fly from Portland International Airport (PDX) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane PDX - ATL
    3. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    10h 31m
    $261–401
  8. Bus, train via Chicago

    1. Take the bus from Salem to Portland Curbside Bus Stopbus bus
    2. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    3. Take the train from Pasco Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    5. Take the bus from New York to Knoxvillebus bus
    3d 11h
    $1,121–2,375
  9. Bus, train

    1. Take the bus from Salem to Seattle Bus Stationbus bus
    2. Take the bus from Seattle Bus Station to Vancouverbus bus
    3. Take the train from Vancouver to Toronto Union Stationtrain train
    4. Take the train from Toronto Union Station to New York Penn Stationtrain train
    5. Take the bus from New York to Knoxvillebus bus
    5d 11h
    $1,139–2,196

Portland International Airport (PDX) to Mcghee Tyson Airport (TYS) flights

Calendar84Weekly Planes
Duration7h 31mAverage Duration
Ticket$280Cheapest Price
See schedules

Questions & Answers

What companies run services between Salem, OR, USA and Knoxville, TN, USA?

There is no direct connection from Salem to Knoxville. However, you can take the bus to Portland International Airport, walk to Portland International Airport (PDX) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Salem to Knoxville via Portland, Chicago Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 3d 11h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound