There are 5 ways to get from Salisbury to Florence by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Florence Regional Airport (FLO)plane SBY - FLO
4h 41m$91–408Drive 423.4 mi
cheapest- Drive from Salisbury to Florencecar 423.4 mi
8h 16m$78–112Bus, train
- Take the bus from Salisbury, MD to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Washington Union Stationtrain
- Take the train from Washington Union Station to Florence Stationtrain
11h 53m$158–870Bus
- Take the bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtownbus
- Take the bus from Baltimore Downtown Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Florence Bus Stationbus
13h 34m$148–240Bus, train via Fayetteville
- Take the bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtownbus
- Take the bus from Baltimore Downtown Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Florence Stationtrain
13h 51m$166–260
Salisbury to Florence by bus and train
Questions & Answers
The cheapest way to get from Salisbury to Florence is to drive which costs $75 - $120 and takes 8h 16m.
The fastest way to get from Salisbury to Florence is to fly which takes 4h 41m and costs $90 - $410.
No, there is no direct bus from Salisbury to Florence station. However, there are services departing from Salisbury, MD and arriving at Florence Bus Station via Baltimore Downtown Bus Station and Raleigh Bus Station. The journey, including transfers, takes approximately 13h 34m.
The distance between Salisbury and Florence is 381 miles. The road distance is 425.9 miles.
The best way to get from Salisbury to Florence without a car is to bus and train which takes 11h 53m and costs $150 - $900.
It takes approximately 4h 41m to get from Salisbury to Florence, including transfers.
Salisbury to Florence bus services, operated by BayRunner Shuttle, depart from Salisbury, MD station.
The best way to get from Salisbury to Florence is to fly which takes 4h 41m and costs $90 - $410. Alternatively, you can bus, which costs $140 - $240 and takes 13h 34m.
Salisbury to Florence bus services, operated by BayRunner Shuttle, arrive at Baltimore, MD - Greyhound Bus Terminal Downtown station.
Yes, the driving distance between Salisbury to Florence is 426 miles. It takes approximately 8h 16m to drive from Salisbury to Florence.
What companies run services between Salisbury, MD, USA and Florence, SC, USA?
American Airlines flies from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Salisbury, MD to Florence Bus Station via Baltimore, MD - Greyhound Bus Terminal Downtown, Baltimore Downtown Bus Station, and Raleigh Bus Station in around 13h 34m.
- Website
- aa.com
Flights from Salisbury–Ocean City–Wicomico Regional Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $60–370
Flights from Salisbury–Ocean City–Wicomico Regional Airport to Florence Regional Airport via Philadelphia, Charlotte
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $75–420
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- Amtrak
Train from Washington Union Station to Florence Station
- Ave. Duration
- 7h 48m
- Frequency
- Twice daily
- Estimated price
- $120–270
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Florence Station
- Ave. Duration
- 1h 46m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- Maryland Transit
- Standard Fare
- $2–9
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 26 min
- Frequency
- 5 times a day
- Estimated price
- $6–550
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $6–440
- First Class
- $100–550
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtown
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtown
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–50
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Raleigh Bus Station
- Ave. Duration
- 5h 50m
- Frequency
- 5 times a day
- Estimated price
- $40–85
- Website
- Greyhound
Bus from Raleigh Bus Station to Florence Bus Station
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Baltimore Downtown Bus Station to Raleigh Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
Bus from Baltimore Downtown Bus Station to Fayetteville Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- $55–95
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Salisbury to Florence bus tickets online with Omio.
There are 48+ hotels available in Florence.
















