There are 7 ways to get from Salisbury to Louisville by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Salisbury–Ocean City–Wicomico Regional Airport
best- Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Louisville International Airport (SDF)plane SBY - SDF
6h 13m$132–628Drive 696.7 mi
cheapest- Drive from Salisbury to Louisvillecar 696.7 mi
12h 27m$128–184Bus via Pittsburgh
- Take the bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtownbus
- Take the bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus
19h 30m$176–305Bus, train
- Take the bus from Salisbury, MD to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Washington Union Stationtrain
- Take the train from Washington Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
25h 46m$279–1,125Bus to Baltimore-Washington International Airport, fly
- Take the bus from Salisbury, MD to BWI-Thurgood Marshall Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane BWI - SDF
6h 1m$188–706Bus, train to Ronald Reagan Washington National Airport, fly
- Take the bus from Salisbury, MD to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane DCA - SDF
7h 34m$182–1,460Bus
- Take the bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtownbus
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
- Take the bus from Harrisburg Bus Station to Cincinnatibus
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
20h 42m$188–320
Salisbury to Louisville by bus
Questions & Answers
The cheapest way to get from Salisbury to Louisville is to drive which costs $120 - $190 and takes 12h 27m.
The fastest way to get from Salisbury to Louisville is to bus and fly which takes 6h 1m and costs $180 - $750.
No, there is no direct bus from Salisbury to Louisville station. However, there are services departing from Salisbury, MD and arriving at Louisville, KY Bus Station via Baltimore Downtown Bus Station, Pittsburgh Intermodal Station and N Wilson Rd & Ferrell Pl - Columbus. The journey, including transfers, takes approximately 19h 30m.
The distance between Salisbury and Louisville is 570 miles. The road distance is 700.8 miles.
The best way to get from Salisbury to Louisville without a car is to bus via Pittsburgh which takes 19h 30m and costs $170 - $310.
It takes approximately 6h 13m to get from Salisbury to Louisville, including transfers.
Salisbury to Louisville bus services, operated by BayRunner Shuttle, depart from Salisbury, MD station.
The best way to get from Salisbury to Louisville is to fly which takes 6h 13m and costs $130 - $650. Alternatively, you can bus via Pittsburgh, which costs $170 - $310 and takes 19h 30m.
Salisbury to Louisville bus services, operated by BayRunner Shuttle, arrive at Baltimore, MD - Greyhound Bus Terminal Downtown station.
Yes, the driving distance between Salisbury to Louisville is 701 miles. It takes approximately 12h 27m to drive from Salisbury to Louisville.
What companies run services between Salisbury, MD, USA and Louisville, KY, USA?
American Airlines flies from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Louisville International Airport (SDF) 3 times a day. Alternatively, you can take a bus from Salisbury, MD to Louisville, KY Bus Station via Baltimore, MD - Greyhound Bus Terminal Downtown, Baltimore Downtown Bus Station, Pittsburgh Intermodal Station, and N Wilson Rd & Ferrell Pl - Columbus in around 19h 30m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Louisville International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $100–600
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–950
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 16m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
- Website
- aa.com
Flights from Salisbury–Ocean City–Wicomico Regional Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $110–600
Flights from Salisbury–Ocean City–Wicomico Regional Airport to Louisville International Airport via Philadelphia
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Ronald Reagan Washington National Airport to Louisville International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $140–850
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $170–950
- Website
- delta.com
Flights from Baltimore-Washington International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 3h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $180–950
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- Amtrak
Train from Washington Union Station to Indianapolis
- Ave. Duration
- 18h 16m
- Frequency
- 3 times a week
- Estimated price
- $220–480
- Website
- Amtrak
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- Amtrak
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- Maryland Transit
- Standard Fare
- $2–9
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- Maryland Transit
- Standard Fare
- $2–9
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 26 min
- Frequency
- 5 times a day
- Estimated price
- $6–550
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $6–440
- First Class
- $100–550
Train from BWI Thurgood Marshall to Washington Union Station
- Ave. Duration
- 26 min
- Frequency
- 5 times a day
- Estimated price
- $6–550
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $6–440
- First Class
- $100–550
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtown
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to BWI-Thurgood Marshall Airport
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtown
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- $85–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 5h 40m
- Frequency
- Every 4 hours
- Estimated price
- $40–80
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 4h 5m
- Frequency
- Every 4 hours
- Estimated price
- $29–55
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $11–22
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Baltimore Downtown Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $40–75
- Schedules at
- Flixbus USA
Bus from Harrisburg Bus Station to Cincinnati
- Ave. Duration
- 10h 50m
- Frequency
- Once daily
- Estimated price
- $80–140
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Station
- Ave. Duration
- 4h 5m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- Barons Bus
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- Barons Bus
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–50
- Website
- Amtrak
Bus from Salisbury, MD to BWI Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–50
- Website
- Amtrak
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Salisbury to Louisville bus tickets online with Omio.
There are 509+ hotels available in Louisville.





















