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How to get fromSalisbury to St. Louisby plane, bus (Greyhound), bus, train, or car

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There are 7 ways to get from Salisbury to St. Louis by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Salisbury–Ocean City–Wicomico Regional Airport

    best
    1. Fly from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Lambert–St. Louis International Airport (STL)plane plane SBY - STL
    6h 4m
    $154–678

  2. Bus

    1. Take the bus from Salisbury, MD to Baltimore, MD - Greyhound Bus Terminal Downtownbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus
    24h 30m
    $218–373

  3. Bus, train via Washington

    1. Take the bus from Salisbury, MD to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Washington Union Stationtrain train
    3. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    27h 53m
    $370–1,294

  4. Drive 905.7 mi

    1. Drive from Salisbury to St. Louiscar car 905.7 mi
    16h 12m
    $166–239

  5. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Salisbury, MD to BWI-Thurgood Marshall Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    6h 3m
    $220–756

  6. Bus, train to Ronald Reagan Washington National Airport, fly

    1. Take the bus from Salisbury, MD to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    7h 23m
    $205–991

  7. Bus, train

    1. Take the bus from Salisbury, MD to BWI Amtrak Stationbus bus
    2. Take the train from Baltimore Penn Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    35h 30m
    $428–1,441

Salisbury to St. Louis by bus

Calendar7Weekly Buses
Duration24h 30mAverage Duration
Ticket$218Cheapest Price
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Questions & Answers

Map of how to get from Salisbury to St. Louis.ExpandLaunch map view
  • Distance: 821.8 mi
  • Duration: 6h 4m

What companies run services between Salisbury, MD, USA and St. Louis, MO, USA?

American Airlines flies from Salisbury–Ocean City–Wicomico Regional Airport (SBY) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a bus from Salisbury, MD to St Louis Bus Station via Baltimore, MD - Greyhound Bus Terminal Downtown, Baltimore Downtown Bus Station, and Harrisburg Bus Station in around 24h 30m.

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