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How to get fromSalisbury to Buffaloby train, plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 8 ways to get from Salisbury to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Charlotte Douglas International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)plane plane CLT - BUF
    5h 35m
    $142–763

  2. Bus

    cheapest
    1. Take the bus from Salisbury to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Cleveland, OHbus bus
    4. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    17h 2m
    $80–212

  3. Train (Amtrak)

    1. Take the train from Salisbury Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    22h
    $318–656

  4. Drive 629.6 mi

    1. Drive from Salisbury to Buffalocar car 629.6 mi
    11h 3m
    $115–166

  5. Train to Raleigh-Durham International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Salisbury Amtrak Station to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    6h 56m
    $159–523

  6. Train to Charlotte Douglas International Airport, fly to Rochester, bus

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Rochester (ROC)plane plane CLT - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 51m
    $179–827

  7. Fly Concord to Rochester, bus

    1. Fly from Concord (USA) to Rochester (ROC)plane plane USA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 22m
    $264–718

  8. Train, bus

    1. Take the train from Salisbury Amtrak Station to Greensborotrain train
    2. Take the bus from Greensboro Bus Stop to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus
    4. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    23h 36m
    $141–383

Salisbury to Buffalo by train (Amtrak)

Calendar14Weekly Trains
Duration22hAverage Duration
Ticket$318Cheapest Price
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Questions & Answers

Map of how to get from Salisbury to Buffalo.ExpandLaunch map view
  • Distance: 611.7 mi
  • Duration: 5h 35m

What companies run services between Salisbury, NC, USA and Buffalo, NY, USA?

You can take a vehicle from Salisbury to Buffalo, NY via Salisbury, Winston Salem(Trans Center), Charleston, WV, and Cleveland, OH in around 17h 2m. Alternatively, you can take a train from Salisbury Amtrak Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 22h.

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