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How to get fromSalisbury to Chicagoby train, plane, bus (Greyhound, Amtrak), train (Amtrak), car, or bus

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There are 10 ways to get from Salisbury to Chicago by train, plane, bus (Greyhound, Amtrak), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Charlotte Douglas International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    5h 56m
    $142–449

  2. Train, bus

    cheapest
    1. Take the train from Salisbury Amtrak Station to High Pointtrain train
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    21h 16m
    $78–198

  3. Bus

    1. Take the bus from Salisbury to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Chicago Union Stationbus bus
    21h 4m
    $187–325

  4. Train (Amtrak)

    1. Take the train from Salisbury Amtrak Station to Carytrain train Piedmont / ...
    2. Take the train from Cary to Chicago Union Stationtrain train Floridian
    28h 32m
    $379–830

  5. Drive 717.5 mi

    1. Drive from Salisbury to Chicagocar car 717.5 mi
    12h 46m
    $131–190

  6. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Salisbury Amtrak Station to High Pointtrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    5h 42m
    $109–453

  7. Train to Charlotte Douglas International Airport, fly to Chicago Midway International Airport

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    5h 34m
    $102–479

  8. Train to Raleigh-Durham International Airport, fly to Chicago Midway International Airport

    1. Take the train from Salisbury Amtrak Station to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Chicago Midway International Airport (MDW)plane plane RDU - MDW
    6h 53m
    $190–380

  9. Train to Charlotte Douglas International Airport, fly to South Bend, train

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    3. Take the train from South Bend Airport to Van Buren St.train train
    7h 54m
    $143–699

  10. Train to Charlotte Douglas International Airport, fly to General Mitchell International Airport, train

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane plane CLT - MKE
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 2m
    $169–808

Salisbury to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration28h 32mAverage Duration
Ticket$379Cheapest Price
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Questions & Answers

Map of how to get from Salisbury to Chicago.ExpandLaunch map view
  • Distance: 668.4 mi
  • Duration: 5h 56m

What companies run services between Salisbury, NC, USA and Chicago, IL, USA?

You can take a vehicle from Salisbury to Chicago Union Station via Salisbury, Charlotte Bus Station, and Toledo in around 21h 4m. Alternatively, you can take a train from Salisbury Amtrak Station to Chicago Union Station via Cary in around 28h 32m.

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