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How to get fromSalisbury to Indianapolisby train, plane, bus (Greyhound), bus, car, or train (Amtrak)

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There are 8 ways to get from Salisbury to Indianapolis by train, plane, bus (Greyhound), bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Charlotte Douglas International Airport, fly to Indianapolis

    best
    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Indianapolis (IND)plane plane CLT - IND
    5h 38m
    $121–636

  2. Bus

    cheapest
    1. Take the bus from Salisbury to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus to Indianapolis Union Stationbus bus
    16h 17m
    $78–167

  3. Train, bus

    1. Take the train from Salisbury Amtrak Station to High Pointtrain train
    2. Take the bus from Winston Salem(Trans Center) to Ashlandbus bus
    3. Take the train from Ashland Amtrak Station to Indianapolistrain train
    17h 32m
    $125–278

  4. Drive 540.7 mi

    1. Drive from Salisbury to Indianapoliscar car 540.7 mi
    9h 43m
    $99–143

  5. Train to Raleigh-Durham International Airport, fly to Indianapolis

    1. Take the train from Salisbury Amtrak Station to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Indianapolis (IND)plane plane RDU - IND
    7h 24m
    $134–627

  6. Train to Concord, fly to Indianapolis

    1. Take the train from Salisbury Amtrak Station to Kannapolistrain train
    2. Fly from Concord (USA) to Indianapolis (IND)plane plane USA - IND
    4h 16m
    $207–567

  7. Train to Charlotte Douglas International Airport, fly to Blue Grass Airport, drive

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    3. Drive from Lexington-Airport-LEX to Indianapoliscar car
    7h 30m
    $169–884

  8. Train (Amtrak)

    1. Take the train from Salisbury Amtrak Station to Charlottesvilletrain train Crescent
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    21h
    $261–545

Salisbury to Indianapolis by train and bus

Calendar3Weekly Services
Duration17h 32mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Salisbury to Indianapolis.ExpandLaunch map view
  • Distance: 493.7 mi
  • Duration: 5h 38m

What companies run services between Salisbury, NC, USA and Indianapolis, IN, USA?

You can take a vehicle from Salisbury to Indianapolis Union Station via Salisbury, Winston Salem(Trans Center), and Columbus in around 16h 17m. Alternatively, you can take a train from Salisbury Amtrak Station to Indianapolis via Charlottesville in around 21h.

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