Rome2Rio

How to get fromSalisbury to Louisvilleby train, plane, bus (Greyhound), bus, or car

Find Transport to Louisville

See all options

There are 6 ways to get from Salisbury to Louisville by train, plane, bus (Greyhound), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Louisville International Airport

    best
    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Louisville International Airport (SDF)plane plane CLT - SDF
    5h 31m
    $110–637

  2. Bus

    cheapest
    1. Take the bus from Salisbury to Winston Salem(Trans Center)bus bus
    2. Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    16h 42m
    $72–172

  3. Train, bus (Amtrak)

    1. Take the train from Salisbury Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 25m
    $271–590

  4. Drive 431.4 mi

    1. Drive from Salisbury to Louisvillecar car 431.4 mi
    9h 5m
    $79–114

  5. Train, fly to Blue Grass Airport, drive

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Blue Grass Airport (LEX)plane plane CLT - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 41m
    $152–903

  6. Train, bus via Atlanta

    1. Take the train from Salisbury Amtrak Station to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus bus
    4. Take the bus from Nashville to Louisville, KYbus bus
    16h 51m
    $117–224

Salisbury to Louisville by train and bus (Amtrak)

Calendar3Weekly Services
Duration24h 25mAverage Duration
Ticket$271Cheapest Price
See schedules

Questions & Answers

Map of how to get from Salisbury to Louisville.ExpandLaunch map view
  • Distance: 393.3 mi
  • Duration: 5h 31m

What companies run services between Salisbury, NC, USA and Louisville, KY, USA?

You can take a vehicle from Salisbury to Louisville, KY Bus Station via Salisbury, Winston Salem(Trans Center), and Columbus - Downtown - Mound St in around 16h 42m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers