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How to get fromSalta to Santiagoby plane, bus, or car

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There are 8 ways to get from Salta to Santiago by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Martín Miguel De Güemes International Airport

    best
    1. Fly from Martín Miguel De Güemes International Airport (SLA) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane SLA - SCL
    7h 23m
    $134–457

  2. Bus

    cheapest
    1. Take the bus from Terminal de Salta to Terminal Mendozabus bus
    2. Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus bus Santiago
    26h 54m
    $70–169

  3. Drive 1,505.3 km

    1. Drive from Salta to Santiagocar car 1,505.3 km
    21h 12m
    $186–269

  4. Bus to Teniente General Benjamín Matienzo International Airport, fly

    1. Take the bus from Terminal Rosario de La Frontera to Terminal de Tucumánbus bus
    2. Fly from Teniente General Benjamín Matienzo International Airport (TUC) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane TUC - SCL
    9h 33m
    $151–522

  5. Bus to Gobernador Horacio Guzmán International Airport, fly

    1. Take the bus from Terminal de Omnibus de General Guemes to Pericobus bus
    2. Fly from Gobernador Horacio Guzmán International Airport (JUJ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane JUJ - SCL
    8h 23m
    $167–481

  6. Bus via E. Cornejo Saravia y Mariano Boedo

    1. Take the bus from Terminal de Salta to Terminal Mendozabus bus Salta
    2. Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus bus Santiago
    28h 21m
    $70–187

  7. Bus via Los Andes

    1. Take the bus from Terminal de Salta to Terminal Mendozabus bus
    2. Take the bus from Terminal Mendoza to Los Andesbus bus
    3. Take the bus from Los Andes to Terminal Los Héroesbus bus
    28h 29m
    $73–216

  8. Bus via Villa Media Agua

    1. Take the bus from Terminal de Salta to Media Aguabus bus
    2. Take the bus from Media Agua to Terminal Mendozabus bus
    3. Take the bus from Terminal Mendoza to Terminal Alameda - Turbusbus bus
    30h 27m
    $82–195

Salta to Santiago by bus

Calendar17Weekly Buses
Duration26h 54mAverage Duration
Ticket$70Cheapest Price
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Questions & Answers

Map of how to get from Salta to Santiago.ExpandLaunch map view
  • Distance: 1,105.1 km
  • Duration: 7h 23m

What companies run services between Salta, Argentina and Santiago, Chile?

Aerolíneas Argentinas, LATAM Chile, and two other airlines fly from Martín Miguel De Güemes International Airport (SLA) to Comodoro Arturo Merino Benítez International Airport (SCL) 3 times a day. Alternatively, you can take a bus from Mitre 373 - Entre Santiago del Estero y Gral. M. M. de Guemes to Terminal Sur de Santiago via Chiclana y Av. H. Yrigoyen, Terminal de Salta, and Terminal Mendoza in around 26h 54m.

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