There are 6 ways to get from San Antonio to La Serena by bus, plane, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from San Antonio - Barrancas to Terminal Alameda - Turbusbus
- Fly from Comodoro Arturo Merino Benítez International Airport (SCL) to La Florida Airport (LSC)plane SCL - LSC
4h 37m$58–117Bus #2
cheapest- Take the bus from San Antonio to Terminal Rodoviario Valparaisobus FlixBus CL014
- Take the bus from Terminal Rodoviario Valparaiso to Terminal de buses La Serenabus Valparaiso / ...
8h 50m$17–88Bus
- Take the bus from San Antonio - Barrancas to Terminal Alameda - Turbusbus Santiago / ...
- Take the bus from Terminal Alameda - Turbus to Terminal de Buses de Coquimbobus Santiago
8h 33m$27–154Drive 487 km
- Drive from San Antonio to La Serenacar 487 km
5h 25m$61–87Bus via Melipilla
- Take the bus from San Antonio - Barrancas to Melipillabus
- Take the bus from Terminal de Buses de Melipilla to Terminal San Borjabus
- Take the bus from Batuco to Terminal de buses La Serenabus
8h 45m$24–49Bus #3
- Take the bus from San Antonio - Barrancas to Terminal Alameda - Turbusbus Santiago / ...
- Take the bus from Santiago to Terminal de buses La Serenabus FlixBus CL040 / ...
8h 50m$59–94
San Antonio to La Serena by bus
Questions & Answers
The cheapest way to get from San Antonio to La Serena is to bus via Melipilla which costs $23 - $50 and takes 8h 45m.
The fastest way to get from San Antonio to La Serena is to bus and fly which takes 4h 37m and costs $55 - $120.
No, there is no direct bus from San Antonio to La Serena. However, there are services departing from San Antonio - Barrancas and arriving at Terminal de buses La Serena via Terminal Alameda - Turbus and Terminal de Buses de Coquimbo. The journey, including transfers, takes approximately 8h 33m.
The distance between San Antonio and La Serena is 518 km. The road distance is 487 km.
The best way to get from San Antonio to La Serena without a car is to bus which takes 8h 33m and costs $26 - $160.
It takes approximately 4h 37m to get from San Antonio to La Serena, including transfers.
San Antonio to La Serena bus services, operated by Pullman Bus Costa Central, depart from San Antonio - Barrancas station.
San Antonio to La Serena bus services, operated by Pullman Bus Costa Central, arrive at Terminal Alameda - Turbus station.
Yes, the driving distance between San Antonio to La Serena is 487 km. It takes approximately 5h 25m to drive from San Antonio to La Serena.
Book your San Antonio to La Serena bus tickets online with Omio.
What companies run services between San Antonio, Chile and La Serena, Chile?
You can take a bus from San Antonio - Barrancas to Terminal de buses La Serena via Terminal Alameda - Turbus and Terminal de Buses de Coquimbo in around 8h 33m.
- Website
- latam.com
Flights from Comodoro Arturo Merino Benítez International Airport to La Florida Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $40–95
- Website
- skyairline.com
Flights from Comodoro Arturo Merino Benítez International Airport to La Florida Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $17–80
- Website
- jetsmart.com
Flights from Comodoro Arturo Merino Benítez International Airport to La Florida Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $26–75
- Phone
- +56 233048912
- [email protected]
- Website
- pullmanbus.cl
Bus from San Antonio - Barrancas to Terminal Alameda - Turbus
- Ave. Duration
- 1h 40m
- Frequency
- Every 10 minutes
- Estimated price
- $9
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
Bus from San Antonio - Barrancas to Terminal Alameda - Turbus
- Ave. Duration
- 1h 40m
- Frequency
- Every 10 minutes
- Estimated price
- $9
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
Bus from San Antonio - Barrancas to Terminal Alameda - Turbus
- Ave. Duration
- 1h 40m
- Frequency
- Every 10 minutes
- Estimated price
- $9
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Alameda - Turbus to Terminal de Buses de Coquimbo
- Semi Cama
- $17–24
- Cama
- $24–35
- Premium
- $60–75
Bus from Terminal Rodoviario Valparaiso to Terminal de buses La Serena
- Semi Cama
- $16–23
- Cama
- $22–30
- Premium
- $60–75
Bus from San Antonio - Barrancas to Melipilla
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Phone
- +56 2 2832 3801
- Website
- chilepasajes.cl
Bus from Terminal de Buses de Melipilla to Terminal San Borja
- Ave. Duration
- 1h
- Frequency
- Every 15 minutes
- Estimated price
- $3
- Book at
- chilepasajes.cl
- Phone
- +56 9 6190 6054
- [email protected]
- Website
- busesvamos.cl
Bus from Terminal de Buses de Melipilla to Terminal San Borja
- Ave. Duration
- 1h
- Frequency
- Every 20 minutes
- Estimated price
- $2–5
- Book at
- busesvamos.cl
Bus from Terminal de Buses de Melipilla to Terminal San Borja
- Ave. Duration
- 1h 7m
- Frequency
- Twice daily
- Estimated price
- $2–4
- Schedules at
- Ruta Bus 78
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Batuco to Terminal de buses La Serena
- Ave. Duration
- 5h 58m
- Frequency
- Every 20 minutes
- Estimated price
- $14–27
- Book at
- Recorrido Pluss Chile
- Semi Cama
- $14–19
- Cama
- $20–27
- Website
- Flixbus Chile
Bus from San Antonio to Terminal Rodoviario Valparaiso
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $8–14
- Schedules at
- Flixbus Chile
Bus from Santiago to Terminal de buses La Serena
- Ave. Duration
- 6h 10m
- Frequency
- Hourly
- Estimated price
- $50–85
- Schedules at
- Flixbus Chile
- Phone
- +56 51 221 5300
- [email protected]
- Website
- Buses Romani
Bus from Terminal Rodoviario Valparaiso to Terminal de buses La Serena
- Ave. Duration
- 6h 30m
- Frequency
- Every 4 hours
- Estimated price
- $9–24
- Schedules at
- Buses Romani
- Semi
- $9–11
- Salon
- $19–24
Bus from Terminal Rodoviario Valparaiso to Terminal de buses La Serena
- Ave. Duration
- 6h 55m
- Frequency
- 3 times a day
- Estimated price
- $11–24
- Schedules at
- Condor Bus
- Semi Cama
- $11–19
- Cama
- $22–24
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Rodoviario Valparaiso to Terminal de buses La Serena
- Ave. Duration
- 7h 50m
- Frequency
- 3 times a week
- Estimated price
- $23–40
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $23–40
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Thanksgiving 2018: How to travel stress-free, Need to know: Eurostar, and Which side of Niagara Falls should I choose (and how do I get there)? - to help you get the most out of your next trip.
More Questions & Answers
There are 964+ hotels available in La Serena.





















