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How to get fromSan Antonio to Florenceby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 5 ways to get from San Antonio to Florence by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from San Antonio International Airport (SAT) to Florence Regional Airport (FLO)plane plane SAT - FLO
    6h 29m
    $131–614

  2. Bus via Sandy Springs

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    25h 58m
    $208–315

  3. Train, bus

    1. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    40h 17m
    $445–970

  4. Drive 1,269.7 mi

    1. Drive from San Antonio to Florencecar car 1,269.7 mi
    20h 42m
    $232–335

  5. Bus

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    28h
    $195–382

San Antonio to Florence by train, foot, tram, and bus

Calendar3Weekly Services
Duration40h 17mAverage Duration
Ticket$445Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Florence.ExpandLaunch map view
  • Distance: 1,155.3 mi
  • Duration: 6h 29m

What companies run services between San Antonio, TX, USA and Florence, SC, USA?

American Airlines flies from San Antonio International Airport (SAT) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from San Antonio Bus Station to Florence Bus Station via Houston Bus Station, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, and Atlanta Bus Station in around 25h 58m.

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