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How to get fromSan Antonio to Great Lakesby plane, bus, train (Amtrak), or car

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There are 7 ways to get from San Antonio to Great Lakes by plane, bus, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to General Mitchell International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to General Mitchell International Airport (MKE)plane plane SAT - MKE
    5h 33m
    $171–801

  2. Bus to Austin-Bergstrom International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Chicago O'Hare International Airport (ORD)plane plane AUS - ORD
    6h 55m
    $116–461

  3. Bus

    1. Take the bus from Tornado Bus Co - San Antonio to Chicagobus bus Querétaro
    25h 30m
    $184–344

  4. Train (Amtrak)

    1. Take the train from San Antonio Station to Chicago Union Stationtrain train Texas Eagle
    31h 13m
    $419–856

  5. Drive 1,193.8 mi

    1. Drive from San Antonio to Chicagocar car 1,193.8 mi
    19h 53m
    $218–315

  6. Fly San Antonio International Airport to Chicago O'Hare International Airport

    1. Fly from San Antonio International Airport (SAT) to Chicago O'Hare International Airport (ORD)plane plane SAT - ORD
    5h 7m
    $173–556

  7. Bus to Austin-Bergstrom International Airport, fly to General Mitchell International Airport

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to General Mitchell International Airport (MKE)plane plane AUS - MKE
    5h 56m
    $174–826

San Antonio to Great Lakes by bus

Calendar7Weekly Buses
Duration25h 30mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Great Lakes.ExpandLaunch map view
  • Distance: 1,105.2 mi
  • Duration: 5h 33m

What companies run services between San Antonio, TX, USA and Great Lakes, MI, USA?

Southwest Airlines, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to General Mitchell International Airport (MKE) every 2 hours. Alternatively, Tornado Bus Company operates a bus from Tornado Bus Co - San Antonio to Chicago once daily. Tickets cost $180–340 and the journey takes 23h 15m.

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