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How to get fromSan Antonio to Jefferson Cityby plane, bus (Greyhound, Flixbus), train (Amtrak), car, shuttle, or bus

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There are 6 ways to get from San Antonio to Jefferson City by plane, bus (Greyhound, Flixbus), train (Amtrak), car, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to Columbia Regional Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Columbia Regional Airport (COU)plane plane SAT - COU
    5h 55m
    $181–571

  2. Drive 822.7 mi

    cheapest
    1. Drive from San Antonio to Jefferson Citycar car 822.7 mi
    13h 38m
    $151–217

  3. Bus

    1. Take the bus from San Antonio Bus Station to Dallas Bus Stationbus bus
    2. Take the bus from Dallas Bus Station to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City Bus Station to Jefferson Citybus bus
    21h 48m
    $158–296

  4. Train (Amtrak)

    1. Take the train from San Antonio Station to St. Louistrain train Texas Eagle
    2. Take the train from St. Louis to Jefferson City Stationtrain train Missouri River Runner / ...
    28h 7m
    $360–751

  5. Fly San Antonio International Airport to Lambert–St. Louis International Airport, shuttle

    1. Fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL)plane plane SAT - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    6h 28m
    $266–851

  6. Bus to Austin-Bergstrom International Airport, fly to Columbia Regional Airport

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Columbia Regional Airport (COU)plane plane AUS - COU
    7h 46m
    $189–586

San Antonio to Jefferson City by train (Amtrak)

Calendar10Weekly Trains
Duration28h 7mAverage Duration
Ticket$360Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Jefferson City.ExpandLaunch map view
  • Distance: 765.2 mi
  • Duration: 5h 55m

What companies run services between San Antonio, TX, USA and Jefferson City, MO, USA?

American Airlines and United Airlines fly from San Antonio International Airport (SAT) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from San Antonio Bus Station to Jefferson City via Dallas Bus Station, Kansas City Bus Station, and Jefferson City in around 21h 48m.

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