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How to get fromSan Antonio to Knoxvilleby plane, train, taxi, bus, shuttle, or car

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There are 6 ways to get from San Antonio to Knoxville by plane, train, taxi, bus, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to Mcghee Tyson Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Mcghee Tyson Airport (TYS)plane plane SAT - TYS
    5h 40m
    $246–1,021

  2. Fly San Antonio International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from San Antonio International Airport (SAT) to Asheville Regional Airport (AVL)plane plane SAT - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 52m
    $133–586

  3. Train, taxi, bus, shuttle, drive

    1. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    3. Take the taxi from Davidson Gateway Dr & Griffith St to Hickory Airporttaxi taxi
    4. Take the bus from Hickory Airport to Blowing Rock - Tanger Outletsbus bus
    5. Take the taxi from Blowing Rock - Tanger Outlets to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    44h 57m
    $917–1,515

  4. Drive 1,109.7 mi

    1. Drive from San Antonio to Knoxvillecar car 1,109.7 mi
    17h 41m
    $203–293

  5. Bus to Austin-Bergstrom International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Mcghee Tyson Airport (TYS)plane plane AUS - TYS
    5h 54m
    $249–996

  6. Fly San Antonio International Airport to Nashville, drive

    1. Fly from San Antonio International Airport (SAT) to Nashville (BNA)plane plane SAT - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 23m
    $481–1,551

San Antonio International Airport (SAT) to Mcghee Tyson Airport (TYS) flights

Calendar93Weekly Planes
Duration4h 58mAverage Duration
Ticket$194Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Knoxville.ExpandLaunch map view
  • Distance: 967.5 mi
  • Duration: 5h 40m

What companies run services between San Antonio, TX, USA and Knoxville, TN, USA?

Southwest Airlines, United Airlines, and two other airlines fly from San Antonio International Airport (SAT) to Mcghee Tyson Airport (TYS) hourly.

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