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How to get fromSan Antonio to La Crosseby plane, bus, train (Amtrak), car, or train

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There are 9 ways to get from San Antonio to La Crosse by plane, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to La Crosse

    best
    1. Fly from San Antonio International Airport (SAT) to La Crosse (LSE)plane plane SAT - LSE
    7h 4m
    $150–624
  2. Bus

    1. Take the bus from Tornado Bus Co - San Antonio to Chicagobus bus
    2. Take the bus from Tornado Bus Co - Chicago to Water & Chicago - Circle Kbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    32h 20m
    $271–556
  3. Train (Amtrak)

    1. Take the train from San Antonio Station to Chicago Union Stationtrain train Texas Eagle
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    37h
    $500–1,045
  4. Drive 1,191.9 mi

    1. Drive from San Antonio to La Crossecar car 1,191.9 mi
    20h 56m
    $218–315
  5. Bus to Austin-Bergstrom International Airport, fly to La Crosse

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to La Crosse (LSE)plane plane AUS - LSE
    9h 8m
    $153–649
  6. Fly San Antonio International Airport to Minneapolis–Saint Paul International Airport, train

    1. Fly from San Antonio International Airport (SAT) to Minneapolis–Saint Paul International Airport (MSP)plane plane SAT - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 42m
    $943–1,189
  7. Fly San Antonio International Airport to Rochester, bus

    1. Fly from San Antonio International Airport (SAT) to Rochester (RST)plane plane SAT - RST
    2. Take the bus from Rochester to La Crossebus bus
    10h 52m
    $150–681
  8. Fly San Antonio International Airport to Dane County Regional Airport-Truax Field, bus

    1. Fly from San Antonio International Airport (SAT) to Dane County Regional Airport-Truax Field (MSN)plane plane SAT - MSN
    2. Take the bus from Madison to La Crossebus bus
    10h 15m
    $218–908
  9. Bus via Broken Arrow

    1. Take the bus from San Antonio to Tulsabus bus
    2. Take the bus from Tulsa to St. Paulbus bus
    3. Take the bus from St. Paul to La Crossebus bus
    32h 58m
    $387–483

San Antonio to La Crosse by train (Amtrak)

Calendar10Weekly Trains
Duration37hAverage Duration
Ticket$500Cheapest Price
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Questions & Answers

What companies run services between San Antonio, TX, USA and La Crosse, WI, USA?

American Airlines and United Airlines fly from San Antonio International Airport (SAT) to La Crosse (LSE) every 4 hours. Alternatively, you can take a bus from St Marys Btwn Market & Villita to La Crosse via I-35 N Access & Marek St, Tornado Bus Co - San Antonio, Tornado Bus Co - Chicago, Water & Chicago - Circle K, and Milwaukee in around 32h 20m.

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