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How to get fromSan Antonio to La Mesaby plane, bus (Greyhound), train, bus, or car

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There are 5 ways to get from San Antonio to La Mesa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Antonio International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to San Diego International Airport (SAN)plane plane SAT - SAN
    5h 40m
    $365–771

  2. Bus to Austin-Bergstrom International Airport, fly

    cheapest
    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to San Diego International Airport (SAN)plane plane AUS - SAN
    7h 32m
    $168–446

  3. Bus

    1. Take the bus from San Antonio, TX - Tornado Bus Co to El Paso, TX - Tornado Bus Cobus bus
    2. Take the bus from El Paso Bus Station to Phoenix Bus Stationbus bus
    3. Take the bus from Phoenix Bus Station to El Cajon Transit Centerbus bus
    25h 39m
    $206–461

  4. Train, bus

    1. Take the train from San Antonio Station to Yuma Amtraktrain train
    2. Take the bus from 3rd Street @ Gila Street to William Brook Ave @ B Streetbus bus 95
    3. Take the bus from San Luis Río Colorado to Mexicalibus bus
    4. Take the bus from Mexicali to Tijuanabus bus
    31h 7m
    $396–894

  5. Drive 1,264.9 mi

    1. Drive from San Antonio to La Mesacar car 1,264.9 mi
    19h 2m
    $231–334

San Antonio International Airport (SAT) to San Diego International Airport (SAN) flights

Calendar50Weekly Planes
Duration4h 38mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to La Mesa.ExpandLaunch map view
  • Distance: 1,153.8 mi
  • Duration: 5h 40m

What companies run services between San Antonio, TX, USA and La Mesa, CA, USA?

Southwest Airlines and American Airlines fly from San Antonio International Airport (SAT) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from St Marys Btwn Market & Villita to La Mesa Blvd Station via I-35 N Access & Marek St, San Antonio, TX - Tornado Bus Co, El Paso, TX - Tornado Bus Co, El Paso Bus Station, Phoenix Bus Station, El Cajon Transit Center, and El Cajon Station in around 25h 39m.

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