There are 6 ways to get from San Antonio to Lafayette by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound, Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from San Antonio Bus Station to Lafayettebus FlixBus 2212
7h 20m$60–100Train (Amtrak)
- Take the train from San Antonio Station to Lafayette Amtrak Stationtrain Sunset Limited
10h 47m$130–280Drive 409.4 mi
- Drive from San Antonio to Lafayettecar 409.4 mi
6h 39m$75–108Fly from San Antonio International Airport
- Fly from San Antonio International Airport (SAT) to Lafayette Regional Airport (LFT)plane SAT - LFT
4h 53m$72–414Bus via Houston
- Take the bus from San Antonio Bus Station to Houston Bus Stationbus Greyhound US1110 / ...
- Take the bus from Houston - Harrisburg Blvd to Lafayettebus Houston
8h 10m$90–136Bus to Austin-Bergstrom International Airport, fly
- Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus
- Fly from Austin-Bergstrom International Airport (AUS) to Lafayette Regional Airport (LFT)plane AUS - LFT
6h 39m$80–409
San Antonio to Lafayette by bus (Flixbus)
Questions & Answers
The cheapest way to get from San Antonio to Lafayette is to bus which costs $60 - $100 and takes 7h 20m.
The fastest way to get from San Antonio to Lafayette is to fly which takes 4h 53m and costs $70 - $420.
Yes, there is a direct bus departing from San Antonio Bus Station station and arriving at Lafayette. Services depart five times a week, and operate Monday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 7h 20m.
Yes, there is a direct train departing from San Antonio Station station and arriving at Lafayette Amtrak Station station. Services depart three times a week, and operate Wednesday, Friday and Sunday. The journey takes approximately 10h 47m.
The distance between San Antonio and Lafayette is 412 miles. The road distance is 411.8 miles.
The best way to get from San Antonio to Lafayette without a car is to bus which takes 7h 20m and costs $60 - $100.
The bus from San Antonio Bus Station to Lafayette takes 7h 20m including transfers and departs five times a week.
San Antonio to Lafayette bus services, operated by Flixbus USA, depart from San Antonio Bus Station.
San Antonio to Lafayette train services, operated by Amtrak, depart from San Antonio Station.
The best way to get from San Antonio to Lafayette is to bus which takes 7h 20m and costs $60 - $100. Alternatively, you can train, which costs $130 - $280 and takes 10h 47m, you could also fly, which costs $70 - $420 and takes 4h 53m.
What companies run services between San Antonio, TX, USA and Lafayette, LA, USA?
Flixbus USA operates a bus from San Antonio Bus Station to Lafayette 5 times a week. Tickets cost $60–100 and the journey takes 7h 20m. Alternatively, Amtrak operates a train from San Antonio Station to Lafayette Amtrak Station 3 times a week. Tickets cost $130–280 and the journey takes 10h 47m.
- Website
- united.com
Flights from San Antonio International Airport to Lafayette Regional Airport via Houston
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $60–400
Flights from Austin-Bergstrom International Airport to Lafayette Regional Airport via Houston
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $55–370
- Website
- aa.com
Flights from San Antonio International Airport to Lafayette Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $80–450
Flights from Austin-Bergstrom International Airport to Lafayette Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $70–420
- Website
- delta.com
Flights from San Antonio International Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $140–650
Flights from Austin-Bergstrom International Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $130–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Antonio Station to Lafayette Amtrak Station
- Ave. Duration
- 10h 47m
- Frequency
- 3 times a week
- Estimated price
- $130–280
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Antonio Bus Station to Lafayette
- Ave. Duration
- 7h 20m
- Frequency
- 5 times a week
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from San Antonio Bus Station to Austin Eastside Bus Plaza
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $12–20
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- 4 times a day
- Estimated price
- $29–60
- Website
- Greyhound
Bus from San Antonio Bus Station to Austin Eastside Bus Plaza
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $11–23
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Houston - Harrisburg Blvd to Lafayette
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- Omnibus Express
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More Questions & Answers
San Antonio to Lafayette bus services, operated by Flixbus USA, arrive at Lafayette station.
San Antonio to Lafayette train services, operated by Amtrak, arrive at Lafayette Amtrak Station.
Yes, the driving distance between San Antonio to Lafayette is 412 miles. It takes approximately 6h 39m to drive from San Antonio to Lafayette.
Book your San Antonio to Lafayette train tickets online with Omio.
Book your San Antonio to Lafayette bus tickets online with Omio and FlixBus.
There are 147+ hotels available in Lafayette.










