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How to get fromSan Antonio to Lake Cityby plane, bus, bus (Greyhound, Flixbus), train, or car

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There are 9 ways to get from San Antonio to Lake City by plane, bus, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to Jacksonville, bus

    best
    1. Fly from San Antonio International Airport (SAT) to Jacksonville (JAX)plane plane SAT - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    9h 12m
    $511–1,322

  2. Fly San Antonio International Airport to Gainesville Regional Airport, bus

    cheapest
    1. Fly from San Antonio International Airport (SAT) to Gainesville Regional Airport (GNV)plane plane SAT - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 57m
    $131–617

  3. Bus

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus Greyhound US1110 / ...
    2. Take the bus from Houston - Harrisburg Blvd to Lake Citybus bus Houston
    18h 53m
    $170–240

  4. Train, bus

    1. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    3. Take the bus from Mobile to Lake Citybus bus
    26h 2m
    $298–580

  5. Drive 1,004.9 mi

    1. Drive from San Antonio to Lake Citycar car 1,004.9 mi
    16h 17m
    $184–265

  6. Bus to Austin-Bergstrom International Airport, fly to Jacksonville, bus

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Jacksonville (JAX)plane plane AUS - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    9h 19m
    $144–647

  7. Fly San Antonio International Airport to Orlando, bus

    1. Fly from San Antonio International Airport (SAT) to Orlando (MCO)plane plane SAT - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    10h 24m
    $208–950

  8. Fly San Antonio International Airport to Valdosta, bus

    1. Fly from San Antonio International Airport (SAT) to Valdosta (VLD)plane plane SAT - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    11h 19m
    $145–609

  9. Bus via Tallahassee

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Lake City Bus Stationbus bus
    23h 5m
    $155–297

San Antonio to Lake City by bus

Calendar14Weekly Buses
Duration23h 5mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Lake City.ExpandLaunch map view
  • Distance: 1,092.4 mi
  • Duration: 9h 12m

What companies run services between San Antonio, TX, USA and Lake City, FL, USA?

You can take a bus from San Antonio Bus Station to Lake City via Houston Bus Station, Houston - Harrisburg Blvd, and Lake City in around 18h 53m.

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