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How to get fromSan Antonio to Lexingtonby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 6 ways to get from San Antonio to Lexington by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Antonio International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Columbia (CAE)plane plane SAT - CAE
    5h 56m
    $319–1,436

  2. Drive 1,180.1 mi

    cheapest
    1. Drive from San Antonio to Lexingtoncar car 1,180.1 mi
    19h 9m
    $216–312

  3. Bus via Sandy Springs

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston - Harrisburg Blvd to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus Nyc
    26h 33m
    $256–385

  4. Train, bus

    1. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus Nyc
    39h 45m
    $503–1,044

  5. Bus to Austin-Bergstrom International Airport, fly

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Columbia (CAE)plane plane AUS - CAE
    8h 13m
    $322–1,461

  6. Bus

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus Nyc
    28h 35m
    $243–452

San Antonio International Airport (SAT) to Columbia (CAE) flights

Calendar90Weekly Planes
Duration5h 45mAverage Duration
Ticket$297Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Lexington.ExpandLaunch map view
  • Distance: 1,079.6 mi
  • Duration: 5h 56m

What companies run services between San Antonio, TX, USA and Lexington, SC, USA?

Delta, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to Columbia (CAE) hourly. Alternatively, you can take a bus from San Antonio Bus Station to Lexington via Houston Bus Station, Houston - Harrisburg Blvd, Atlanta, Doraville Station, Garnett Station, Atlanta Bus Station, Camden, and Columbia, SC in around 26h 33m.

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