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How to get fromSan Antonio to Louisvilleby plane, bus (Greyhound, Flixbus, Amtrak), train, bus, or car

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There are 8 ways to get from San Antonio to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to Louisville International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Louisville International Airport (SDF)plane plane SAT - SDF
    6h 40m
    $382–954

  2. Bus to Austin-Bergstrom International Airport, fly to Louisville International Airport

    cheapest
    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Louisville International Airport (SDF)plane plane AUS - SDF
    8h 18m
    $165–779

  3. Bus via Irving

    1. Take the bus from San Antonio Bus Station to Dallas Bus Stationbus bus
    2. Take the bus from Dallas Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    23h 40m
    $172–330

  4. Train, bus

    1. Take the train from San Antonio Station to St. Louistrain train
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    32h 22m
    $385–774

  5. Drive 1,095.1 mi

    1. Drive from San Antonio to Louisvillecar car 1,095.1 mi
    17h 51m
    $200–289

  6. Fly San Antonio International Airport to Blue Grass Airport, drive

    1. Fly from San Antonio International Airport (SAT) to Blue Grass Airport (LEX)plane plane SAT - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    7h 31m
    $254–1,220

  7. Fly San Antonio International Airport to Nashville, bus

    1. Fly from San Antonio International Airport (SAT) to Nashville (BNA)plane plane SAT - BNA
    2. Take the bus from Nashville to Louisville, KYbus bus
    8h 52m
    $483–1,553

  8. Bus

    1. Take the bus from Tornado Bus Co - San Antonio to Tornado Bus Co - West Memphisbus bus Nuevo Laredo / ...
    2. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus Memphis
    24h 22m
    $187–444

San Antonio to Louisville by bus

Calendar14Weekly Buses
Duration23h 40mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Louisville.ExpandLaunch map view
  • Distance: 957.3 mi
  • Duration: 6h 40m

What companies run services between San Antonio, TX, USA and Louisville, KY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from San Antonio International Airport (SAT) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from San Antonio Bus Station to Louisville, KY via Dallas Bus Station and Nashville in around 23h 40m.

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