There are 5 ways to get from San Antonio to Port Isabel by bus, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from San Antonio to Brownsvillebus Dallas
6h 51m$72–90Drive 286.8 mi
cheapest- Drive from San Antonio to Port Isabelcar 286.8 mi
5h 3m$53–76Fly to Brownsville-South Padre Island International Airport
- Fly from San Antonio International Airport (SAT) to Brownsville-South Padre Island International Airport (BRO)plane SAT - BRO
6h 25m$78–463Bus via San Antonio Bus Station (Flixbus)
- Take the bus from San Antonio Bus Station to La Plaza at Brownsvillebus FlixBus US1120 / ...
9h$59–85Fly to Rio Grande Valley International Airport, bus
- Fly from San Antonio International Airport (SAT) to Rio Grande Valley International Airport (HRL)plane SAT - HRL
- Take the bus from Harlingen Bus Station to Brownsvillebus
8h 58m$115–505
San Antonio International Airport (SAT) to Brownsville-South Padre Island International Airport (BRO) flights
Comparing Your Travel Options
The cheapest way to get from San Antonio to Port Isabel is to drive which costs $50 - $80 and takes 5h 3m.
The fastest way to get from San Antonio to Port Isabel is to drive which takes 5h 3m and costs $50 - $80.
No, there is no direct bus from San Antonio to Port Isabel. However, there are services departing from San Antonio and arriving at Las Palmas Port Isabel via Brownsville. The journey, including transfers, takes approximately 6h 51m.
The distance between San Antonio and Port Isabel is 330 miles. The road distance is 288.5 miles.
The best way to get from San Antonio to Port Isabel without a car is to bus which takes 6h 51m and costs $70 - $90.
It takes approximately 6h 51m to get from San Antonio to Port Isabel, including transfers.
San Antonio to Port Isabel bus services, operated by Omnibus Express, depart from San Antonio station.
The best way to get from San Antonio to Port Isabel is to bus which takes 6h 51m and costs $70 - $90. Alternatively, you can fly, which costs $75 - $470 and takes 6h 25m.
San Antonio to Port Isabel bus services, operated by Omnibus Express, arrive at Brownsville station.
Yes, the driving distance between San Antonio to Port Isabel is 288 miles. It takes approximately 5h 3m to drive from San Antonio to Port Isabel.
What companies run services between San Antonio, TX, USA and Port Isabel, TX, USA?
Omnibus Express operates a bus from San Antonio to Brownsville once daily. Tickets cost $70–90 and the journey takes 5h 11m. Alternatively, United Airlines and American Airlines fly from San Antonio International Airport (SAT) to Brownsville-South Padre Island International Airport (BRO) every 4 hours.
- Website
- southwest.com
Flights from San Antonio International Airport to Rio Grande Valley International Airport via Houston Hobby Apt
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $75–450
Flights from San Antonio International Airport to Rio Grande Valley International Airport via Dallas
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $90–550
- Website
- united.com
Flights from San Antonio International Airport to Brownsville-South Padre Island International Airport via Houston
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $75–460
Flights from San Antonio International Airport to Rio Grande Valley International Airport via Houston
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $75–460
- Website
- aa.com
Flights from San Antonio International Airport to Brownsville-South Padre Island International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 8m
- When
- Monday, Wednesday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $95–550
Flights from San Antonio International Airport to Rio Grande Valley International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $90–550
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from San Antonio to Brownsville
- Ave. Duration
- 5h 11m
- Frequency
- Once daily
- Estimated price
- $70–90
- Schedules at
- Omnibus Express
Bus from Harlingen Bus Station to Brownsville
- Ave. Duration
- 25 min
- Frequency
- Once daily
- Estimated price
- $35–50
- Schedules at
- Omnibus Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Antonio Bus Station to La Plaza at Brownsville
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Schedules at
- Flixbus USA
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Booking & Getting There
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