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How to get fromSan Antonio to Saint Charlesby plane, bus (Flixbus, Amtrak), train (Amtrak), car, or bus

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There are 5 ways to get from San Antonio to Saint Charles by plane, bus (Flixbus, Amtrak), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Antonio International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL)plane plane SAT - STL
    4h 36m
    $135–705

  2. Bus

    1. Take the bus from Tornado Bus Co - San Antonio to Marathon Gas Station - Marionbus bus Querétaro
    2. Take the bus from Carbondale Intermodal Station to St Louis Bus Stationbus bus FlixBus N2521
    24h 35m
    $193–383

  3. Train (Amtrak)

    1. Take the train from San Antonio Station to St. Louistrain train Texas Eagle
    26h 7m
    $333–679

  4. Drive 899.4 mi

    1. Drive from San Antonio to Saint Charlescar car 899.4 mi
    14h 59m
    $165–238

  5. Bus to Austin-Bergstrom International Airport, fly

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Lambert–St. Louis International Airport (STL)plane plane AUS - STL
    6h 29m
    $368–931

San Antonio to Saint Charles by train and bus (Amtrak)

Calendar10Weekly Services
Duration26h 7mAverage Duration
Ticket$333Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to Saint Charles.ExpandLaunch map view
  • Distance: 809.5 mi
  • Duration: 4h 36m

What companies run services between San Antonio, TX, USA and Saint Charles, MO, USA?

Southwest Airlines, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from St Marys Btwn Market & Villita to 4375 Rider Trail North Sb via I-35 N Access & Marek St, Tornado Bus Co - San Antonio, Marathon Gas Station - Marion, Carbondale Intermodal Station, St Louis Bus Station, Civic Center Transit Center, and North Hanley Transit Center in around 24h 35m.

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