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How to get fromSan Antonio to St. Louis (Region)by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Find Transport to St. Louis (Region)

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There are 5 ways to get from San Antonio to St. Louis (Region) by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from San Antonio International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL)plane plane SAT - STL
    4h 11m
    $134–704

  2. Bus

    1. Take the bus from San Antonio Bus Station to Dentonbus bus
    2. Take the bus from Denton to Oklahoma City Bus Stationbus bus
    3. Take the bus from Oklahoma City Bus Station to St Louis Bus Stationbus bus
    21h 45m
    $155–288

  3. Train (Amtrak)

    1. Take the train from San Antonio Station to St. Louistrain train Texas Eagle
    24h 42m
    $330–700

  4. Drive 901.7 mi

    1. Drive from San Antonio to St. Louis (Region)car car 901.7 mi
    14h 52m
    $165–238

  5. Bus to Austin-Bergstrom International Airport, fly

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Lambert–St. Louis International Airport (STL)plane plane AUS - STL
    6h 4m
    $367–930

San Antonio to St. Louis (Region) by bus

Calendar7Weekly Buses
Duration21h 45mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from San Antonio to St. Louis (Region).ExpandLaunch map view
  • Distance: 809.4 mi
  • Duration: 4h 11m

What companies run services between San Antonio, TX, USA and St. Louis (Region), MO, USA?

Southwest Airlines, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from San Antonio Bus Station to St Louis Bus Station via Denton and Oklahoma City Bus Station in around 21h 45m.

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