There are 7 ways to get from San Antonio to Texas Medical Center by bus (Flixbus), train (Amtrak), car, plane, bus, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from San Antonio Bus Station to Downtown Houstonbus FlixBus 2212
3h 35m$33–53Bus via Houston Bus Station
cheapest- Take the bus from San Antonio Bus Station to Houston Bus Stationbus Greyhound US1110 / ...
4h 32m$31–59Train (Amtrak)
- Take the train from San Antonio Station to Houstontrain Sunset Limited
5h 22m$70–141Drive 196 mi
- Drive from San Antonio to Texas Medical Centercar 196 mi
3h 11m$36–52Fly to George Bush Intercontinental Airport, line 500 bus
- Fly from San Antonio International Airport (SAT) to George Bush Intercontinental Airport (IAH)plane SAT - IAH
- Take the bus from Bush IAH Term E - Downtown Direct to Travis St @ St. Joseph Pkwybus
4h 10m$55–377Bus #2 (Greyhound)
- Take the bus from San Antonio Bus Station to Houston Bus Stationbus Via Laredo
5h 13m$37–62Fly to William P. Hobby Airport, line 297 bus
- Fly from San Antonio International Airport (SAT) to William P. Hobby Airport (HOU)plane SAT - HOU
- Take the bus from Monroe Park & Ride to Bertner Ave @ Wilkins Stbus
4h 2m$94–656
San Antonio to Texas Medical Center by bus, foot, and tram (Flixbus)
Questions & Answers
The cheapest way to get from San Antonio to Texas Medical Center is to bus which costs $30 - $55 and takes 3h 35m.
The fastest way to get from San Antonio to Texas Medical Center is to drive which takes 3h 11m and costs $35 - $55.
No, there is no direct bus from San Antonio station to Texas Medical Center. However, there are services departing from San Antonio Bus Station and arriving at Downtown Houston via . The journey, including transfers, takes approximately 3h 35m.
No, there is no direct train from San Antonio station to Texas Medical Center. However, there are services departing from San Antonio Station and arriving at Dryden/Tmc Stn SB via Downtown Transit Center Stn SB. The journey, including transfers, takes approximately 5h 22m.
The distance between San Antonio and Texas Medical Center is 199 miles. The road distance is 197.1 miles.
The best way to get from San Antonio to Texas Medical Center without a car is to bus which takes 3h 35m and costs $30 - $55.
It takes approximately 3h 35m to get from San Antonio to Texas Medical Center, including transfers.
San Antonio to Texas Medical Center bus services, operated by Flixbus USA, depart from San Antonio Bus Station.
San Antonio to Texas Medical Center train services, operated by Amtrak, depart from San Antonio Station.
The best way to get from San Antonio to Texas Medical Center is to bus which takes 3h 35m and costs $30 - $55. Alternatively, you can train, which costs $70 - $150 and takes 5h 22m.
What companies run services between San Antonio, TX, USA and Texas Medical Center, TX, USA?
Flixbus USA operates a bus from San Antonio Bus Station to Downtown Houston once daily. Tickets cost $30–55 and the journey takes 3h 10m. Alternatively, Amtrak operates a train from San Antonio Station to Houston 3 times a week. Tickets cost $65–140 and the journey takes 4h 45m.
- Website
- united.com
Flights from San Antonio International Airport to George Bush Intercontinental Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $50–370
- Website
- southwest.com
Flights from San Antonio International Airport to William P. Hobby Airport
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- $90–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Antonio Station to Houston
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a week
- Estimated price
- $65–140
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from San Antonio Bus Station to Downtown Houston
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1 713-635-4000
- Website
- ridemetro.org
Bus from Bush IAH Term E - Downtown Direct to Travis St @ St. Joseph Pkwy
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- $2–5
- Website
- https://www.ridemetro.org
Bus from Monroe Park & Ride to Bertner Ave @ Wilkins St
- Ave. Duration
- 25 min
- Frequency
- Every 2 hours
- Estimated price
- $1–3
- Website
- https://www.ridemetro.org
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
- Phone
- +1-800-231-2222
- [email protected]
- Website
- greyhound.com.mx
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $30–60
- Schedules at
- greyhound.com.mx
Want to know more about travelling around United States
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More Questions & Answers
San Antonio to Texas Medical Center bus services, operated by Flixbus USA, arrive at Downtown Houston station.
San Antonio to Texas Medical Center train services, operated by Amtrak, arrive at Houston station.
Yes, the driving distance between San Antonio to Texas Medical Center is 197 miles. It takes approximately 3h 11m to drive from San Antonio to Texas Medical Center.
There are 2130+ hotels available in Texas Medical Center.















