There are 8 ways to get from San Antonio to Winston-Salem by plane, bus (Greyhound, Flixbus), bus, train, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly San Antonio International Airport to Piedmont Triad International Airport
best- Fly from San Antonio International Airport (SAT) to Piedmont Triad International Airport (GSO)plane SAT - GSO
7h 3m$220–974Fly San Antonio International Airport to Raleigh-Durham International Airport, bus
cheapest- Fly from San Antonio International Airport (SAT) to Raleigh-Durham International Airport (RDU)plane SAT - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
8h 34m$159–1,030Bus
- Take the bus from San Antonio Bus Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus
28h$195–392Bus, train
- Take the bus from San Antonio Bus Station to New Orleans Bus Stationbus FlixBus 2212
- Take the train from New Orleans Union Passenger Terminal to High Pointtrain Crescent
33h 35m$360–746Drive 1,292.8 mi
- Drive from San Antonio to Winston-Salemcar 1,292.8 mi
21h 41m$236–341Fly San Antonio International Airport to Charlotte Douglas International Airport, bus
- Fly from San Antonio International Airport (SAT) to Charlotte Douglas International Airport (CLT)plane SAT - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
7h 31m$182–897Bus to Austin-Bergstrom International Airport, fly to Piedmont Triad International Airport
- Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus
- Fly from Austin-Bergstrom International Airport (AUS) to Piedmont Triad International Airport (GSO)plane AUS - GSO
9h$233–999Train (Amtrak)
- Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain Sunset Limited
- Take the train from New Orleans Union Passenger Terminal to High Pointtrain Crescent
38h 49m$455–982
San Antonio to Winston-Salem by bus
Questions & Answers
The cheapest way to get from San Antonio to Winston-Salem is to fly and bus which costs $150 - $1,100 and takes 8h 34m.
The fastest way to get from San Antonio to Winston-Salem is to fly which takes 7h 3m and costs $220 - $1,000.
No, there is no direct bus from San Antonio station to Winston-Salem. However, there are services departing from San Antonio Bus Station and arriving at Winston Salem(Trans Center) via Houston Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 28h.
No, there is no direct train from San Antonio station to Winston-Salem. However, there are services departing from San Antonio Station and arriving at High Point via New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 38h 49m.
The distance between San Antonio and Winston-Salem is 1205 miles. The road distance is 1300.4 miles.
The best way to get from San Antonio to Winston-Salem without a car is to bus which takes 28h and costs $190 - $400.
It takes approximately 7h 3m to get from San Antonio to Winston-Salem, including transfers.
San Antonio to Winston-Salem bus services, operated by Greyhound USA, depart from San Antonio Bus Station.
San Antonio to Winston-Salem train services, operated by Amtrak, depart from San Antonio Station.
The best way to get from San Antonio to Winston-Salem is to fly which takes 7h 3m and costs $220 - $1,000. Alternatively, you can bus, which costs $190 - $400 and takes 28h, you could also train, which costs $450 - $1,000 and takes 38h 49m.
What companies run services between San Antonio, TX, USA and Winston-Salem, NC, USA?
Delta, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from San Antonio Bus Station to Winston Salem(Trans Center) via Houston Bus Station and Atlanta Bus Station in around 28h.
- Website
- delta.com
Flights from San Antonio International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $200–950
Flights from San Antonio International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 9h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,200
Flights from San Antonio International Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $180–850
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $200–950
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 8h 40m
- When
- Every day
- Estimated price
- $260–1,100
Flights from San Antonio International Airport to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $150–700
- Website
- aa.com
Flights from San Antonio International Airport to Piedmont Triad International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $210–950
Flights from San Antonio International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $200–950
Flights from San Antonio International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $260–1,100
Flights from San Antonio International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $170–850
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $200–950
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $210–950
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 8h 8m
- When
- Every day
- Estimated price
- $260–1,100
Flights from San Antonio International Airport to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $150–700
- Website
- southwest.com
Flights from San Antonio International Airport to Charlotte Douglas International Airport via Dallas
- Ave. Duration
- 5h 1m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $180–850
Flights from San Antonio International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 4h 37m
- When
- Sunday
- Estimated price
- $180–850
Flights from San Antonio International Airport to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 4h 36m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $150–700
- Website
- united.com
Flights from San Antonio International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 6h 14m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $260–1,100
Flights from San Antonio International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $260–1,100
Flights from San Antonio International Airport to Charlotte Douglas International Airport via Houston
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $180–850
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Austin-Bergstrom International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $260–1,100
- Website
- flybreeze.com
Flights from San Antonio International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 3h 5m
- When
- Thursday and Sunday
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to High Point
- Ave. Duration
- 20h 51m
- Frequency
- Once daily
- Estimated price
- $270–600
- Website
- Amtrak
Train from San Antonio Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 15h 15m
- Frequency
- 3 times a week
- Estimated price
- $180–380
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to High Point
- Ave. Duration
- 20h 51m
- Frequency
- Once daily
- Estimated price
- $270–600
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Every 4 hours
- Estimated price
- $30–60
- Website
- Greyhound
Bus from Houston Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 15m
- Frequency
- Every 4 hours
- Estimated price
- $120–240
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–95
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- Greyhound
Bus from San Antonio Bus Station to Austin Eastside Bus Plaza
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $12–23
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Antonio Bus Station to Houston Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from San Antonio Bus Station to New Orleans Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $85–150
- Schedules at
- Flixbus USA
Bus from San Antonio Bus Station to Austin Eastside Bus Plaza
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $12–21
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- Barons Bus
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More Questions & Answers
San Antonio to Winston-Salem bus services, operated by Greyhound USA, arrive at Houston Bus Station.
Winston-Salem is 1h ahead of San Antonio. It is currently 3:25 AM in San Antonio and 4:25 AM in Winston-Salem.
San Antonio to Winston-Salem train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between San Antonio to Winston-Salem is 1300 miles. It takes approximately 21h 41m to drive from San Antonio to Winston-Salem.
Book your San Antonio to Winston-Salem bus tickets online with Omio and FlixBus.
There are 133+ hotels available in Winston-Salem.












