Rome2Rio

How to get fromSan Antonio to Winston-Salemby plane, bus (Greyhound, Flixbus), bus, train, car, or train (Amtrak)

Find Transport to Winston-Salem

See all options

There are 8 ways to get from San Antonio to Winston-Salem by plane, bus (Greyhound, Flixbus), bus, train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly San Antonio International Airport to Piedmont Triad International Airport

    best
    1. Fly from San Antonio International Airport (SAT) to Piedmont Triad International Airport (GSO)plane plane SAT - GSO
    7h 3m
    $220–974
  2. Fly San Antonio International Airport to Raleigh-Durham International Airport, bus

    cheapest
    1. Fly from San Antonio International Airport (SAT) to Raleigh-Durham International Airport (RDU)plane plane SAT - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    8h 34m
    $159–1,030
  3. Bus

    1. Take the bus from San Antonio Bus Station to Houston Bus Stationbus bus
    2. Take the bus from Houston Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    28h
    $195–392
  4. Bus, train

    1. Take the bus from San Antonio Bus Station to New Orleans Bus Stationbus bus FlixBus 2212
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train Crescent
    33h 35m
    $360–746
  5. Drive 1,292.8 mi

    1. Drive from San Antonio to Winston-Salemcar car 1,292.8 mi
    21h 41m
    $236–341
  6. Fly San Antonio International Airport to Charlotte Douglas International Airport, bus

    1. Fly from San Antonio International Airport (SAT) to Charlotte Douglas International Airport (CLT)plane plane SAT - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 31m
    $182–897
  7. Bus to Austin-Bergstrom International Airport, fly to Piedmont Triad International Airport

    1. Take the bus from San Antonio Bus Station to Austin Eastside Bus Plazabus bus
    2. Fly from Austin-Bergstrom International Airport (AUS) to Piedmont Triad International Airport (GSO)plane plane AUS - GSO
    9h
    $233–999
  8. Train (Amtrak)

    1. Take the train from San Antonio Station to New Orleans Union Passenger Terminaltrain train Sunset Limited
    2. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train Crescent
    38h 49m
    $455–982

San Antonio to Winston-Salem by bus

Calendar28Weekly Buses
Duration28hAverage Duration
Ticket$195Cheapest Price
See schedules

Questions & Answers

What companies run services between San Antonio, TX, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from San Antonio International Airport (SAT) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from San Antonio Bus Station to Winston Salem(Trans Center) via Houston Bus Station and Atlanta Bus Station in around 28h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers