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How to get fromSan Diego to Buffaloby plane, train (Amtrak), bus (Greyhound), car, or shuttle

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There are 5 ways to get from San Diego to Buffalo by plane, train (Amtrak), bus (Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Buffalo Niagara International Airport (BUF)plane plane SAN - BUF
    7h 17m
    $285–1,120

  2. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 10h
    $905–2,057

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbusbus bus
    4. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    2d 15h
    $424–848

  4. Drive 2,532.7 mi

    1. Drive from San Diego to Buffalocar car 2,532.7 mi
    41h 44m
    $463–668

  5. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Toronto Pearson International Airport (YYZ)plane plane SAN - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 26m
    $332–1,204

San Diego to Buffalo by train (Amtrak)

Calendar7Weekly Trains
Duration2d 10hAverage Duration
Ticket$905Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Buffalo.ExpandLaunch map view
  • Distance: 2,206.4 mi
  • Duration: 7h 17m

What companies run services between San Diego, CA, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from San Diego International Airport (SAN) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a train from San Diego to Buffalo via Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2d 10h.

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