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How to get fromSan Diego to Buffalo Depew Stationby plane, train (Amtrak), bus (Greyhound), car, shuttle, or train

Find Transport to Buffalo Depew Station

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There are 6 ways to get from San Diego to Buffalo Depew Station by plane, train (Amtrak), bus (Greyhound), car, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Buffalo Niagara International Airport (BUF)plane plane SAN - BUF
    6h 31m
    $256–968

  2. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 9h
    $842–1,917

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus
    4. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    2d 22h
    $443–963

  4. Drive 2,535.8 mi

    1. Drive from San Diego to Buffalo Depew Stationcar car 2,535.8 mi
    41h 46m
    $463–669

  5. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Toronto Pearson International Airport (YYZ)plane plane SAN - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    7h 33m
    $400–1,272

  6. Fly to Rochester, train

    1. Fly from San Diego International Airport (SAN) to Rochester (ROC)plane plane SAN - ROC
    2. Take the train from Rochester to Buffalo Depew Stationtrain train
    8h 34m
    $313–1,261

San Diego to Buffalo Depew Station by train (Amtrak)

Calendar7Weekly Trains
Duration2d 9hAverage Duration
Ticket$842Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Buffalo Depew Station.ExpandLaunch map view
  • Distance: 2,195 mi
  • Duration: 6h 31m

What companies run services between San Diego, CA, USA and Buffalo Depew Station, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from San Diego International Airport (SAN) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a train from San Diego to Buffalo Depew Station via Fullerton Amtrak Station and Chicago Union Station in around 2d 9h.

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