There are 7 ways to get from San Diego to Cambridge by plane, train (Amtrak), bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Boston Logan Airport
best- Fly from San Diego International Airport (SAN) to Boston Logan Airport (BOS)plane SAN - BOS
6h 4m$180–408Fly to Theodore Francis Green State Airport, train
cheapest- Fly from San Diego International Airport (SAN) to Theodore Francis Green State Airport (PVD)plane SAN - PVD
- Take the train from TF Green Airport to Back Baytrain
9h 40m$137–516Train (Amtrak)
- Take the train from San Diego to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
2d 21h$991–2,266Bus
- Take the bus from San Diego to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
3d 3h$499–999Drive 2,944.8 mi
- Drive from San Diego to Cambridgecar 2,944.8 mi
2d 1h$538–777Fly to Manchester Airport, bus
- Fly from San Diego International Airport (SAN) to Manchester Airport (MHT)plane SAN - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
9h 30m$193–745Bus, train
- Take the bus from San Diego to Fullerton Amtrak Stationbus
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
2d 22h$848–1,826
San Diego to Cambridge by train (Amtrak)
Questions & Answers
The cheapest way to get from San Diego to Cambridge is to fly and train which costs $130 - $550 and takes 9h 40m.
The fastest way to get from San Diego to Cambridge is to fly which takes 6h 4m and costs $180 - $410.
No, there is no direct bus from San Diego to Cambridge. However, there are services departing from San Diego and arriving at Boston via Los Angeles Union Station, St Louis Bus Station and New York. The journey, including transfers, takes approximately 3 days 3h.
No, there is no direct train from San Diego to Cambridge. However, there are services departing from San Diego and arriving at Boston via Fullerton Amtrak Station and Chicago Union Station. The journey, including transfers, takes approximately 2 days 21h.
The distance between San Diego and Cambridge is 2608 miles. The road distance is 2962 miles.
The best way to get from San Diego to Cambridge without a car is to train which takes 2 days 21h and costs $950 - $2,300.
It takes approximately 6h 4m to get from San Diego to Cambridge, including transfers.
San Diego to Cambridge bus services, operated by Greyhound Mexico, depart from San Diego station.
San Diego to Cambridge train services, operated by Amtrak, depart from San Diego station.
The best way to get from San Diego to Cambridge is to fly which takes 6h 4m and costs $180 - $410. Alternatively, you can train, which costs $950 - $2,300 and takes 2 days 21h, you could also bus, which costs $490 - $1,000 and takes 3 days 3h.
What companies run services between San Diego, CA, USA and Cambridge, MA, USA?
Alaska Airlines, Inc., JetBlue Airways, and two other airlines fly from San Diego International Airport (SAN) to Boston Logan Airport (BOS) every 3 hours. Alternatively, you can take a train from San Diego to Boston via Fullerton Amtrak Station and Chicago Union Station in around 2d 21h.
- Website
- southwest.com
Flights from San Diego International Airport to Boston Logan Airport
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $170–700
Flights from San Diego International Airport to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $170–700
Flights from San Diego International Airport to Boston Logan Airport via St. Louis
- Ave. Duration
- 7h 10m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $170–700
Flights from San Diego International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 7h 52m
- When
- Monday to Wednesday
- Estimated price
- $170–700
Flights from San Diego International Airport to Manchester Airport via Chicago Midway
- Ave. Duration
- 7h 58m
- When
- Tuesday to Friday
- Estimated price
- $180–750
Flights from San Diego International Airport to Manchester Airport via Nashville
- Ave. Duration
- 7h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–800
Flights from San Diego International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 8h 18m
- When
- Tuesday, Wednesday, Thursday, Sunday, Monday, and Friday
- Estimated price
- $190–750
Flights from San Diego International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 7h 48m
- When
- Wednesday, Thursday, Sunday, Tuesday, and Saturday
- Estimated price
- $130–550
Flights from San Diego International Airport to Theodore Francis Green State Airport via Chicago Midway
- Ave. Duration
- 8h 21m
- When
- Tuesday, Wednesday, Sunday, and Thursday
- Estimated price
- $120–500
Flights from San Diego International Airport to Theodore Francis Green State Airport via Nashville
- Ave. Duration
- 10h 25m
- When
- Monday, Thursday, Friday, and Tuesday
- Estimated price
- $130–550
- Website
- aa.com
Flights from San Diego International Airport to Boston Logan Airport
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $170–400
Flights from San Diego International Airport to Manchester Airport via Chicago O'Hare
- Ave. Duration
- 9h 26m
- When
- Every day
- Estimated price
- $180–750
Flights from San Diego International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 9h 47m
- When
- Every day
- Estimated price
- $190–750
Flights from San Diego International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 9h 38m
- When
- Every day
- Estimated price
- $120–550
- Website
- jetblue.com
Flights from San Diego International Airport to Boston Logan Airport
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $170–700
- Website
- delta.com
Flights from San Diego International Airport to Boston Logan Airport
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $170–700
Flights from San Diego International Airport to Theodore Francis Green State Airport via Detroit
- Ave. Duration
- 10h 3m
- When
- Every day
- Estimated price
- $120–500
- Website
- alaskaair.com
Flights from San Diego International Airport to Boston Logan Airport
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $170–400
- Website
- united.com
Flights from San Diego International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 8h 9m
- When
- Every day
- Estimated price
- $190–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $650–1,500
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 21h 54m
- Frequency
- Once daily
- Estimated price
- $310–700
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $650–1,500
- Website
- Amtrak
Train from TF Green Airport to Back Bay
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $24–40
- Schedules at
- Greyhound Mexico
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Los Angeles Union Station to St Louis Bus Station
- Ave. Duration
- 40h 15m
- Frequency
- Once daily
- Estimated price
- $280–550
- Website
- Greyhound
Bus from St Louis Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 24h 50m
- Frequency
- 3 times a day
- Estimated price
- $150–300
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $45–110
- Website
- Peter Pan
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $30–50
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 17h 5m
- Frequency
- Twice daily
- Estimated price
- $130–220
- Schedules at
- Flixbus USA
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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More Questions & Answers
San Diego to Cambridge bus services, operated by Greyhound Mexico, arrive at Los Angeles Union Station.
Cambridge is 3h ahead of San Diego. It is currently 8:02 PM in San Diego and 11:02 PM in Cambridge.
San Diego to Cambridge train services, operated by Amtrak, arrive at Fullerton Amtrak Station.
Yes, the driving distance between San Diego to Cambridge is 2962 miles. It takes approximately 2 days 1h to drive from San Diego to Cambridge.
Book your San Diego to Cambridge train tickets online with Omio.
Book your San Diego to Cambridge bus tickets online with Omio.
There are 1469+ hotels available in Cambridge.























