There are 6 ways to get from San Diego to Durham by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Raleigh-Durham International Airport
best- Fly from San Diego International Airport (SAN) to Raleigh-Durham International Airport (RDU)plane SAN - RDU
6h 23m$154–626Bus
- Take the bus from San Diego to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Durhambus
2d 11h$413–692Train (Amtrak)
- Take the train from San Diego to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Raleigh Union Stationtrain
3d$788–2,013Drive 2,475.5 mi
- Drive from San Diego to Durhamcar 2,475.5 mi
40h 46m$452–653Fly to Piedmont Triad International Airport, train
- Fly from San Diego International Airport (SAN) to Piedmont Triad International Airport (GSO)plane SAN - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
8h 58m$277–1,055Fly to Charlotte Douglas International Airport, train
- Fly from San Diego International Airport (SAN) to Charlotte Douglas International Airport (CLT)plane SAN - CLT
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
9h 14m$164–404
San Diego to Durham by bus
Comparing Your Travel Options
The cheapest way to get from San Diego to Durham is to fly and train which costs $160 - $410 and takes 9h 14m.
The fastest way to get from San Diego to Durham is to fly which takes 6h 23m and costs $150 - $650.
No, there is no direct bus from San Diego to Durham. However, there are services departing from San Diego and arriving at Durham via Los Angeles Union Station, Dallas Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 2 days 11h.
No, there is no direct train from San Diego to Durham station. However, there are services departing from San Diego and arriving at Raleigh Union Station via Fullerton Amtrak Station and Chicago Union Station. The journey, including transfers, takes approximately 3 days 0h.
The distance between San Diego and Durham is 2218 miles. The road distance is 2489.9 miles.
The best way to get from San Diego to Durham without a car is to bus which takes 2 days 11h and costs $410 - $700.
It takes approximately 6h 23m to get from San Diego to Durham, including transfers.
San Diego to Durham bus services, operated by Flixbus USA, depart from San Diego station.
San Diego to Durham train services, operated by Amtrak, depart from San Diego station.
The best way to get from San Diego to Durham is to fly which takes 6h 23m and costs $150 - $650. Alternatively, you can bus, which costs $410 - $700 and takes 2 days 11h, you could also train, which costs $750 - $2,100 and takes 3 days 0h.
What companies run services between San Diego, CA, USA and Durham, NC, USA?
Alaska Airlines, Inc., Breeze Airways, and two other airlines fly from San Diego International Airport (SAN) to Raleigh-Durham International Airport (RDU) every 4 hours. Alternatively, you can take a bus from San Diego to Durham via Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 11h.
- Website
- aa.com
Flights from San Diego International Airport to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 7h 37m
- When
- Every day
- Estimated price
- $140–650
Flights from San Diego International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 7h 41m
- When
- Every day
- Estimated price
- $230–1,000
Flights from San Diego International Airport to Piedmont Triad International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 30m
- When
- Every day
- Estimated price
- $230–1,000
Flights from San Diego International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 9h 47m
- When
- Every day
- Estimated price
- $240–1,100
Flights from San Diego International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- $25–60
- Website
- Amtrak
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $500–1,300
- Website
- Amtrak
Train from Chicago Union Station to Raleigh Union Station
- Ave. Duration
- 24h 1m
- Frequency
- Once daily
- Estimated price
- $260–650
- Website
- Amtrak
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $13–35
- Website
- Amtrak
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $35–90
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $18–28
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Durham
- Ave. Duration
- 7h 10m
- Frequency
- 3 times a day
- Estimated price
- $55–85
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
San Diego to Durham bus services, operated by Flixbus USA, arrive at Los Angeles Union Station.
Durham is 3h ahead of San Diego. It is currently 1:59 PM in San Diego and 4:59 PM in Durham.
San Diego to Durham train services, operated by Amtrak, arrive at Fullerton Amtrak Station.
Yes, the driving distance between San Diego to Durham is 2490 miles. It takes approximately 40h 46m to drive from San Diego to Durham.
Book your San Diego to Durham train tickets online with Omio.
Book your San Diego to Durham bus tickets online with Omio and FlixBus.
There are 398+ hotels available in Durham.







