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How to get fromSan Diego to Gainesvilleby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 9 ways to get from San Diego to Gainesville by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport

    best
    1. Fly from San Diego International Airport (SAN) to Gainesville Regional Airport (GNV)plane plane SAN - GNV
    8h 3m
    $164–633

  2. Train, bus

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to Houstontrain train
    3. Take the bus from Houston - Harrisburg Blvd to Tallahasseebus bus
    4. Take the bus from Tallahassee to Gainesvillebus bus
    2d 9h
    $688–1,393

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    2d 10h
    $414–788

  4. Drive 2,311.9 mi

    1. Drive from San Diego to Gainesvillecar car 2,311.9 mi
    36h 25m
    $422–610

  5. Fly to Jacksonville, bus

    1. Fly from San Diego International Airport (SAN) to Jacksonville (JAX)plane plane SAN - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    9h 6m
    $189–709

  6. Fly to Orlando, bus

    1. Fly from San Diego International Airport (SAN) to Orlando (MCO)plane plane SAN - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    8h 47m
    $259–901

  7. Fly to Tampa, bus

    1. Fly from San Diego International Airport (SAN) to Tampa (TPA)plane plane SAN - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    9h 29m
    $419–953

  8. Bus, train

    1. Take the bus from San Diego to Los Angelesbus bus
    2. Take the train from Los Angeles to Houstontrain train
    3. Take the bus from Houston Bus Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Gainesvillebus bus
    2d 12h
    $679–1,428

  9. Train, bus via Chicago

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    4. Take the bus from Jacksonville to Gainesvillebus bus
    3d 13h
    $1,245–2,690

San Diego to Gainesville by bus

Calendar14Weekly Buses
Duration2d 10hAverage Duration
Ticket$414Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Gainesville.ExpandLaunch map view
  • Distance: 2,072.3 mi
  • Duration: 8h 3m

What companies run services between San Diego, CA, USA and Gainesville, FL, USA?

Delta and American Airlines fly from San Diego International Airport (SAN) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from San Diego to Gainesville via Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 10h.

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