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How to get fromSan Diego to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 8 ways to get from San Diego to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from San Diego International Airport (SAN) to Mcghee Tyson Airport (TYS)plane plane SAN - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 56m
    $274–1,108

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from San Diego International Airport (SAN) to Asheville Regional Airport (AVL)plane plane SAN - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    8h 33m
    $156–603

  3. Bus, drive (Greyhound)

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    2d 16h
    $433–849

  4. Train, bus, drive

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    3d 6h
    $937–2,052

  5. Drive 2,211.1 mi

    1. Drive from San Diego to Great Smoky Mountainscar car 2,211.1 mi
    36h 30m
    $404–583

  6. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from San Diego International Airport (SAN) to Greenville–Spartanburg International Airport (GSP)plane plane SAN - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    9h 14m
    $231–884

  7. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from San Diego International Airport (SAN) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane SAN - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    8h 27m
    $236–457

  8. Fly to Nashville, drive

    1. Fly from San Diego International Airport (SAN) to Nashville (BNA)plane plane SAN - BNA
    2. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    8h 33m
    $190–580

San Diego International Airport (SAN) to Mcghee Tyson Airport (TYS) flights

Calendar70Weekly Planes
Duration7h 19mAverage Duration
Ticket$263Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 1,958 mi
  • Duration: 7h 56m

What companies run services between San Diego, CA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from San Diego to Great Smoky Mountains. However, you can fly to Mcghee Tyson Airport (TYS) then drive to Great Smoky Mountains. Alternatively, you can take a bus from San Diego to Great Smoky Mountains via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 2d 16h.

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