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How to get fromSan Diego to Indianaby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

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There are 8 ways to get from San Diego to Indiana by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Indianapolis

    best
    1. Fly from San Diego International Airport (SAN) to Indianapolis (IND)plane plane SAN - IND
    5h 6m
    $208–654

  2. Fly to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from San Diego International Airport (SAN) to Chicago O'Hare International Airport (ORD)plane plane SAN - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 7m
    $122–471

  3. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2d 2h
    $410–745

  4. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    2d 4h
    $793–1,697

  5. Drive 2,037.6 mi

    1. Drive from San Diego to Indianapoliscar car 2,037.6 mi
    33h 9m
    $372–538

  6. Fly to Chicago Midway International Airport, train

    1. Fly from San Diego International Airport (SAN) to Chicago Midway International Airport (MDW)plane plane SAN - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 48m
    $143–553

  7. Fly to General Mitchell International Airport, bus, train

    1. Fly from San Diego International Airport (SAN) to General Mitchell International Airport (MKE)plane plane SAN - MKE
    2. Take the bus from Mitchell Airport to O'Hare International Airport - Terminal 2 Departuresbus bus
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    8h
    $234–845

  8. Bus, train

    1. Take the bus from San Diego to Los Angelesbus bus
    2. Take the train from Los Angeles to Bloomington-Normaltrain train
    3. Take the bus from Bloomington to Indianapolisbus bus
    2d 19h
    $890–1,832

San Diego to Indiana by bus

Calendar14Weekly Buses
Duration2d 2hAverage Duration
Ticket$410Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Indiana.ExpandLaunch map view
  • Distance: 1,793.6 mi
  • Duration: 5h 6m

What companies run services between San Diego, CA, USA and Indiana, USA?

Southwest Airlines, United Airlines, and Frontier Airlines fly from San Diego International Airport (SAN) to Indianapolis (IND) every 4 hours. Alternatively, you can take a bus from San Diego to Indianapolis Union Station via Los Angeles Union Station and St Louis Bus Station in around 2d 2h.

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