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How to get fromSan Diego to Jefferson Cityby plane, train (Amtrak), bus (Greyhound), car, or shuttle

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There are 5 ways to get from San Diego to Jefferson City by plane, train (Amtrak), bus (Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia Regional Airport

    best
    1. Fly from San Diego International Airport (SAN) to Columbia Regional Airport (COU)plane plane SAN - COU
    5h 44m
    $211–618

  2. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Kansas Citytrain train
    3. Take the train from Kansas City to Jefferson City Stationtrain train
    41h 57m
    $633–1,377

  3. Bus (Greyhound)

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jefferson Citybus bus
    2d 1h
    $337–650

  4. Drive 1,675.2 mi

    1. Drive from San Diego to Jefferson Citycar car 1,675.2 mi
    29h 31m
    $306–442

  5. Fly to Lambert–St. Louis International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Lambert–St. Louis International Airport (STL)plane plane SAN - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    6h 40m
    $272–374

San Diego to Jefferson City by train (Amtrak)

Calendar7Weekly Trains
Duration41h 57mAverage Duration
Ticket$633Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Jefferson City.ExpandLaunch map view
  • Distance: 1,478.9 mi
  • Duration: 5h 44m

What companies run services between San Diego, CA, USA and Jefferson City, MO, USA?

American Airlines and United Airlines fly from San Diego International Airport (SAN) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a train from San Diego to Jefferson City Station via Fullerton Amtrak Station and Kansas City in around 41h 57m.

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