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How to get fromSan Diego to Key Largoby plane, shuttle, bus, train, bus (Flixbus, Greyhound), or car

Find Transport to Key Largo

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There are 7 ways to get from San Diego to Key Largo by plane, shuttle, bus, train, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Miami International Airport, shuttle

    best
    1. Fly from San Diego International Airport (SAN) to Miami International Airport (MIA)plane plane SAN - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 5m
    $225–584

  2. Fly to Key West International Airport, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Key West International Airport (EYW)plane plane SAN - EYW
    2. Take the bus from Key West Airport to Key Largo Bus Stopbus bus
    11h 30m
    $104–375

  3. Bus, train, shuttle

    1. Take the bus from San Diego to Los Angelesbus bus
    2. Take the train from Los Angeles to Houstontrain train
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the bus from Fort Myers 7-11 to Miami Airportbus bus
    5. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    2d 20h

  4. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    2d 20h
    $550–865

  5. Drive  2,684.9 mi

    1. Drive from San Diego to Key Largocar car 2,684.9 mi
    43h 11m
    $475–686

  6. Fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SAN - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 30m
    $443–1,132

  7. Train, bus

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Hollywood Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    4d
    $2,369–3,809

San Diego to Key Largo by bus

Calendar14Weekly Buses
Duration2d 20hAverage Duration
Ticket$550Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from San Diego to Key Largo.ExpandLaunch map view
  • Distance: 2,321.5 mi
  • Duration: 7h 5m

What companies run services between San Diego, CA, USA and Key Largo, FL, USA?

You can take a bus from San Diego to Key Largo Bus Stop via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and Miami Airport Station in around 2d 20h.

Airlines
Train operators
Bus operators

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