There are 5 ways to get from San Diego to Key West by plane, bus, ferry, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from San Diego International Airport (SAN) to Key West International Airport (EYW)plane SAN - EYW
7h 18m$156–566Bus, ferry
- Take the bus from San Diego to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
2d 18h$645–970Train, bus, ferry
- Take the train from San Diego to Los Angelestrain
- Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
2d 23h$962–1,768Drive 2,782 mi
- Drive from San Diego to Key Westcar 2,782 mi
45h 32m$508–734Train, bus
- Take the train from San Diego to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus
4d 4h$1,439–3,050
San Diego to Key West by train, taxi, bus, and foot
Questions & Answers
The cheapest way to get from San Diego to Key West is to fly which costs $150 - $600 and takes 7h 18m.
The fastest way to get from San Diego to Key West is to fly which takes 7h 18m and costs $150 - $600.
The distance between San Diego and Key West is 2226 miles. The road distance is 2798.3 miles.
The best way to get from San Diego to Key West without a car is to bus and ferry which takes 2 days 18h and costs $600 - $1,000.
It takes approximately 7h 18m to get from San Diego to Key West, including transfers.
Key West is 3h ahead of San Diego. It is currently 11:44 PM in San Diego and 2:44 AM in Key West.
Yes, the driving distance between San Diego to Key West is 2798 miles. It takes approximately 45h 32m to drive from San Diego to Key West.
There are 965+ hotels available in Key West.
What companies run services between San Diego, CA, USA and Key West, FL, USA?
American Airlines and Delta fly from San Diego International Airport (SAN) to Key West International Airport (EYW) every 4 hours.
- Website
- aa.com
Flights from San Diego International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $140–600
Flights from San Diego International Airport to Key West International Airport via Miami
- Ave. Duration
- 7h 59m
- When
- Tuesday to Sunday
- Estimated price
- $150–600
Flights from San Diego International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 10h 3m
- When
- Every day
- Estimated price
- $170–650
- Website
- delta.com
Flights from San Diego International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 8h 46m
- When
- Every day
- Estimated price
- $160–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego to Los Angeles
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- $40–85
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to New Orleans Union Passenger Terminal
- Ave. Duration
- 45h 40m
- Frequency
- 3 times a week
- Estimated price
- $600–1,300
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
Train from San Diego to Fullerton Amtrak Station
- Ave. Duration
- 2h 19m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- https://www.amtrak.com/home.html
Train from Fullerton Amtrak Station to Chicago Union Station
- Ave. Duration
- 42h 47m
- Frequency
- Once daily
- Estimated price
- $700–1,500
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $650–1,400
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $21–35
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from San Diego to Los Angeles Union Station
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $40–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $40–55
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Los Angeles Union Station to Dallas Bus Station
- Ave. Duration
- 29h 5m
- Frequency
- Twice daily
- Estimated price
- $220–430
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to Houston Bus Station
- Ave. Duration
- 4h 39m
- Frequency
- Every 4 hours
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Houston - Harrisburg Blvd to Fort Myers
- Ave. Duration
- 20h 38m
- Frequency
- Once daily
- Estimated price
- $170–220
- Schedules at
- omnibusexpress.com
Bus from Gulfport to Fort Myers
- Ave. Duration
- 13h 17m
- Frequency
- Once daily
- Estimated price
- $120–150
- Schedules at
- omnibusexpress.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Want to know more about travelling around United States
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