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How to get fromSan Diego to Key West (Island)by plane, bus, ferry, train, car, shuttle, or bus (Greyhound, Flixbus)

Find Transport to Key West (Island)

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There are 7 ways to get from San Diego to Key West (Island) by plane, bus, ferry, train, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Key West International Airport

    best
    1. Fly from San Diego International Airport (SAN) to Key West International Airport (EYW)plane plane SAN - EYW
    7h 13m
    $130–550

  2. Bus, ferry

    1. Take the bus from Cross Border Express, San Diego to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston - Harrisburg Blvd to Fort Myersbus bus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    2d 22h
    $597–832

  3. Train, bus, ferry

    1. Take the train from San Diego to Los Angelestrain train
    2. Take the train from Los Angeles to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Fort Myersbus bus
    5. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    2d 23h
    $962–1,869

  4. Drive 2,782 mi

    1. Drive from San Diego to Key Westcar car 2,782 mi
    45h 32m
    $508–734

  5. Fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane SAN - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FLshuttle bus
    10h 15m
    $476–1,387

  6. Fly to Miami International Airport, shuttle

    1. Fly from San Diego International Airport (SAN) to Miami International Airport (MIA)plane plane SAN - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    10h 8m
    $319–671

  7. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Key West Airportbus bus
    3d
    $487–943

San Diego to Key West (Island) by bus

Calendar14Weekly Buses
Duration3dAverage Duration
Ticket$487Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Key West (Island).ExpandLaunch map view
  • Distance: 2,211 mi
  • Duration: 7h 13m

What companies run services between San Diego, CA, USA and Key West (Island), FL, USA?

American Airlines and Delta fly from San Diego International Airport (SAN) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from San Diego to Key West Airport via Los Angeles Union Station, Dallas Bus Station, Atlanta Bus Station, and Miami Airport Station in around 3d.

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