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How to get fromSan Diego to Kirksvilleby plane, train, train (Amtrak), car, or shuttle

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There are 5 ways to get from San Diego to Kirksville by plane, train, train (Amtrak), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Kansas City, train

    best
    1. Fly from San Diego International Airport (SAN) to Kansas City (MCI)plane plane SAN - MCI
    2. Take the train from Kansas City to La Plata Stationtrain train
    8h 39m
    $285–544

  2. Fly to Lambert–St. Louis International Airport, shuttle

    cheapest
    1. Fly from San Diego International Airport (SAN) to Lambert–St. Louis International Airport (STL)plane plane SAN - STL
    2. Take a shuttle bus from St. Louis to Bowling Green, Moshuttle bus
    3. Take a shuttle bus from Bowling Green, Mo to Columbiashuttle bus
    4. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    10h 58m
    $151–245

  3. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train Pacific Surfliner
    2. Take the train from Fullerton Amtrak Station to La Plata Stationtrain train Southwest Chief
    40h 45m
    $677–1,422

  4. Drive 1,701.1 mi

    1. Drive from San Diego to Kirksvillecar car 1,701.1 mi
    30h 19m
    $311–449

  5. Fly to Kirksville Regional Airport

    1. Fly from San Diego International Airport (SAN) to Kirksville Regional Airport (IRK)plane plane SAN - IRK
    7h 19m
    $163–584

San Diego International Airport (SAN) to Kansas City (MCI) flights

Calendar32Weekly Planes
Duration4h 40mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

Map of how to get from San Diego to Kirksville.ExpandLaunch map view
  • Distance: 1,508.6 mi
  • Duration: 8h 39m

What companies run services between San Diego, CA, USA and Kirksville, MO, USA?

You can take a train from San Diego to Kirksville via Fullerton Amtrak Station and La Plata Station in around 40h 45m. Alternatively, Alaska Airlines, Inc., Corporate Flight Management Inc, and two other airlines fly from San Diego International Airport (SAN) to Kirksville Regional Airport (IRK) 3 times a day.

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