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How to get fromSan Diego to La Crosseby plane, train (Amtrak), bus (Greyhound), car, train, or bus

Find Transport to La Crosse

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There are 6 ways to get from San Diego to La Crosse by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to La Crosse

    best
    1. Fly from San Diego International Airport (SAN) to La Crosse (LSE)plane plane SAN - LSE
    8h 23m
    $166–609
  2. Fly to Rochester, bus

    cheapest
    1. Fly from San Diego International Airport (SAN) to Rochester (RST)plane plane SAN - RST
    2. Take the bus from Rochester to La Crossebus bus
    11h 15m
    $155–604
  3. Train (Amtrak)

    1. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train
    2d 4h
    $818–1,757
  4. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Tulsa Bus Stationbus bus
    3. Take the bus from Tulsa to St. Paulbus bus
    4. Take the bus from St. Paul to La Crossebus bus
    2d 7h
    $434–754
  5. Drive 1,966.6 mi

    1. Drive from San Diego to La Crossecar car 1,966.6 mi
    32h 1m
    $359–519
  6. Fly to Minneapolis–Saint Paul International Airport, train

    1. Fly from San Diego International Airport (SAN) to Minneapolis–Saint Paul International Airport (MSP)plane plane SAN - MSP
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train
    8h 1m
    $256–629

San Diego to La Crosse by train (Amtrak)

Calendar7Weekly Trains
Duration2d 4hAverage Duration
Ticket$818Cheapest Price
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Questions & Answers

What companies run services between San Diego, CA, USA and La Crosse, WI, USA?

United Airlines and American Airlines fly from San Diego International Airport (SAN) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from San Diego to La Crosse Amtrak Station via Fullerton Amtrak Station and Chicago Union Station in around 2d 4h.

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