Rome2Rio

How to get fromSan Diego to Lexingtonby plane, car, bus (Greyhound), bus, or train

Find Transport to Lexington

See all options

There are 5 ways to get from San Diego to Lexington by plane, car, bus (Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louisville International Airport, drive

    best
    1. Fly from San Diego International Airport (SAN) to Louisville International Airport (SDF)plane plane SAN - SDF
    2. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 14m
    $218–835
  2. Bus

    1. Take the bus from San Diego to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2d 6h
  3. Bus, train

    1. Take the bus from San Diego to Fullerton Amtrak Stationbus bus
    2. Take the train from Fullerton Amtrak Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    2d 6h
  4. Drive 2,134.2 mi

    1. Drive from San Diego to Lexingtoncar car 2,134.2 mi
    34h 51m
    $390–563
  5. Fly to Blue Grass Airport

    1. Fly from San Diego International Airport (SAN) to Blue Grass Airport (LEX)plane plane SAN - LEX
    8h 22m
    $323–1,266

San Diego International Airport (SAN) to Louisville International Airport (SDF) flights

Calendar50Weekly Planes
Duration7hAverage Duration
Ticket$203Cheapest Price
See schedules

Questions & Answers

What companies run services between San Diego, CA, USA and Lexington, KY, USA?

You can take a bus from San Diego to Lexington via Los Angeles Union Station, St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 2d 6h. Alternatively, American Airlines, United Airlines, and Delta fly from San Diego International Airport (SAN) to Blue Grass Airport (LEX) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers